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Humanized CD19 CAR-T cells in relapsed/refractory B-ALL patients who relapsed after or failed murine CD19 CAR-T therapy

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Published in 2022 at "BMC Cancer"

DOI: 10.1186/s12885-022-09489-1

Abstract: Background For CD19-positive relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) after treatment with murine CD19 (mCD19) CAR-T, the reinfusion of mCD19 CAR-T cells may be ineffective due to anti-mouse single-chain variable fragment (scFv) antibody caused… read more here.

Keywords: car cells; hcd19 car; cd19; humanized cd19 ... See more keywords