Transgenic Expression of hCD47 Minimizes the Development of Proteinuria Following Pig-to-Baboon Kidney Transplantation and Reduces Phagocytosis of Porcine Endothelial Cells and Podocytes
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DOI: 10.1097/01.tp.0000543036.39314.a6
Abstract: Background The early development of proteinuria following pig renal xenotransplantation (XKTx) was a major obstacle to prolonged life-supporting GalTKO XKTx in baboons. We have recently shown that CTLA-4Ig and Rituximab reduce proteinuria in association with… read more here.
Keywords: development proteinuria; hcd47; porcine; expression ... See more keywords