PEGylated Erlotinib HCl Injectable Nanoformulation for Improved Bioavailability
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DOI: 10.1208/s12249-023-02560-5
Abstract: The present study was undertaken to synthesize PEGylated monomethoxy poly (ethylene glycol)-poly (ε-Caprolactone) (mPEG-PCL) block copolymer and formulate Erlotinib HCl–loaded mPEG-PCL nanoparticles for enhancing the bioavailability of the drug. Using the ring-opening polymerization technique, PEGylated… read more here.
Keywords: hcl; bioavailability; erlotinib hcl; hcl loaded ... See more keywords
In vitro and in vivo evaluation of alginate and alginatechitosan beads containing metformin hydrochloride
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DOI: 10.4314/tjpr.v16i2.5
Abstract: Purpose : To prepare metformin HCl-loaded alginate (AL) and alginate-chitosan (AL-CS) beads for oral application and to evaluate their in vitro characteristics and in vivo activities. Methods : AL and AL-CS beads were prepared using… read more here.
Keywords: alginate; metformin hcl; metformin; hcl loaded ... See more keywords
Application of Box-Behnken Experimental Design in Process Parameter Optimization for Production of Berberine HCl loaded Chitosan Coated Sodium Alginate Nanoparticles
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DOI: 10.52711/0974-360x.2023.00190
Abstract: Psoriasis is the most common chronic autoimmune disease. The pathophysiology, genetics, comorbidities, and biologic therapies of plaque psoriasis have seen the most rapid advances. Only a tiny percentage of the supplied dose reaches the target… read more here.
Keywords: loaded chitosan; release; berberine; hcl loaded ... See more keywords