A ratiometric benzothiazole-based fluorescence probe for selectively recognizing HClO and its practical applications
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.03.064
Abstract: Abstract A ratiometric probe (HBT-HBZ) bearing 2-hydrazino benzothiazole and 3-(benzo[d]thiazol-2-yl)-2-hydroxy-5-methylbenzaldehyde for sensing hypochlorous acid (HClO) with high selectivity and sensitivity is reported in this article. The fluorescence intensity ratios (I470 nm/I572 nm) of the probe with different… read more here.
Keywords: microscopy; probe; hclo; practical applications ... See more keywords
A specifically triggered turn-on fluorescent probe platform and its visual imaging of HClO in cells, arthritis and tumors.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2021.127874
Abstract: Understanding disease-related processes at the molecular level is of great importance for the prevention and treatment of diseases. However, due to the lack of effective analytical tools, it is challenging to gain insight into the… read more here.
Keywords: probe; hclo cells; fluorescent probe; hclo ... See more keywords
An endoplasmic reticulum-targeting fluorescent probe for the imaging of hypochlorous acid in living cells and zebrafishes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Photochemistry and Photobiology A: Chemistry"
DOI: 10.1016/j.jphotochem.2019.111980
Abstract: Abstract Hypochlorous acid (HClO) plays critical biological roles in living systems, and abnormal accumulation of HClO could cause oxidative stress and lead to tissue damage and a range of diseases. Herein, we present an endoplasmic… read more here.
Keywords: endoplasmic reticulum; hypochlorous acid; targeting fluorescent; reticulum targeting ... See more keywords
Single Wavelength Laser Excitation Ratiometric NIR-II Fluorescent Probe for Molecule Imaging in Vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c00556
Abstract: Fluorescence (FL) imaging in the second near-infrared window (NIR-II, 1000-1700 nm) has emerged as a promising bioim-aging modality that enables noninvasive visualization of deep-tissue with an unprecedented resolution. However, there is a paucity of studies… read more here.
Keywords: sett; excitation ratiometric; hclo; laser excitation ... See more keywords
Smart Bimodal Imaging of Hypochlorous Acid in Vivo Using a Heterobimetallic Ruthenium(II)-Gadolinium(III) Complex Probe.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c01198
Abstract: A unique heterobimetallic Ru(II)-Gd(III) complex, Ru-AN-Gd, is reported to serve as an effective probe for bimodal phosphorescence-magnetic resonance (MR) imaging of hypochlorous acid (HClO) in vitro and in vivo. The probe was designed by incorporating… read more here.
Keywords: imaging hypochlorous; probe; hclo; phosphorescence ... See more keywords
De Novo Design of a Robust Fluorescent Probe for Basal HClO Imaging in a Mouse Parkinson's Disease Model.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00431
Abstract: Elevated HClO gets involved in the pathogenesis of Parkinson's disease (PD). Herein, a novel fluorescent probe NUU-1 was designed and synthesized. Distinct from the general strategies, NUU-1 features two distinct HClO reactive sites, a HClO-specific… read more here.
Keywords: fluorescent probe; basal hclo; probe; hclo ... See more keywords
A new ratiometric fluorescent probe for detecting endogenous HClO in living cells
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c7nj03907g
Abstract: A new benzimidazole-hemicyanine-based ratiometric fluorescent probe (ZBM-H) was developed, which showed high selectivity and sensitivity for detecting HClO. Furthermore, ZBM-H with a longer wavelength emission (653 nm), good membrane permeability and less cytotoxicity was successfully… read more here.
Keywords: endogenous hclo; hclo; fluorescent probe; ratiometric fluorescent ... See more keywords
Si-rhodamine fluorescent probe for monitoring of hypochlorous acid in the brains of mice afflicted with neuroinflammation.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06475h
Abstract: Neuroinflammation leads to a persistent oxidative stress in the brain, and is closely related to the pathology of various neurological disorders. Hypochlorous acid (HClO) is a reactive oxygen species (ROS) that, at high levels, can… read more here.
Keywords: hypochlorous acid; rhodamine fluorescent; hclo; brains mice ... See more keywords
In Vitro and In Vivo Antimicrobial Activity of Hypochlorous Acid against Drug-Resistant and Biofilm-Producing Strains
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02365-22
Abstract: Currently, drug-resistant infections are increasing and there are fewer antibiotics available to treat them. Therefore, there is an urgent need to find new antibiotics and nonantimicrobial strategies to treat these infections. We present a new… read more here.
Keywords: biofilm producing; hypochlorous acid; producing strains; hclo ... See more keywords