Cytomegalovirus infection and atherosclerosis risk: A meta‐analysis
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DOI: 10.1002/jmv.24858
Abstract: Human cytomegalovirus (HCMV) infection is an important risk factor for atherosclerosis (AS). Numerous studies have been conducted to analyze the association between HCMV infection and risk of AS, but no clear consensus has been reached.… read more here.
Keywords: risk; infection; hcmv; atherosclerosis ... See more keywords
ADAM9: A regulator between HCMV infection and function of smooth muscle cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28352
Abstract: Lots of epidemiological and clinical studies have shown that human cytomegalovirus (HCMV) is related to the pathogenesis of atherosclerosis. Released by inflammatory cells and vascular smooth muscle cell (VSMCs), metalloproteinases are observed in many pathological… read more here.
Keywords: function; hcmv; expression; hcmv infection ... See more keywords
ELISPOT assays with pp65 peptides or whole HCMV antigen are reliable predictors of immune control of HCMV infection in seropositive kidney transplant recipients
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28507
Abstract: Human cytomegalovirus (HCMV) infection represents a major complication for solid organ transplant recipients. The aim of this study was to verify if the measurement of HCMV‐specific T‐cells could help to identify patients protected against HCMV… read more here.
Keywords: cfc idc; hcmv; hcmv infection; transplant recipients ... See more keywords
A systematic review and meta‐analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women
Sign Up to like & getrecommendations! Published in 2022 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2399
Abstract: The detection of human cytomegalovirus (HCMV) in an individual's bodily fluid by culture techniques or through HCMV DNA detection by polymerase chain reaction, is known as HCMV shedding. Human cytomegalovirus shedding has the potential to… read more here.
Keywords: hcmv shedding; hcmv seropositive; infection; hcmv ... See more keywords
The polymorphism at residue 156 determines the HLA-B*35 restricted peptide repertoire during HCMV infection
Sign Up to like & getrecommendations! Published in 2018 at "Immunogenetics"
DOI: 10.1007/s00251-018-1077-z
Abstract: Peptide selection in infected cells is not fully understood yet, but several indications point to the fact that there are differences to uninfected cells, especially in productive HCMV infection, since HCMV evolved various strategies to… read more here.
Keywords: peptide; hcmv; hla; peptide repertoire ... See more keywords
Inhibitory effects of piceatannol on human cytomegalovirus (hCMV) in vitro
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Microbiology"
DOI: 10.1007/s12275-020-9528-2
Abstract: Human cytomegalovirus (hCMV) is a ubiquitous herpesvirus, which results in the establishment of a latent infection that persists throughout the life of the host and can be reactivated when the immunity is low. Currently, there… read more here.
Keywords: infection; hcmv; human cytomegalovirus; cytomegalovirus hcmv ... See more keywords
Characterization of a thienylcarboxamide derivative that inhibits the transactivation functions of cytomegalovirus IE2 and varicella zoster virus IE62
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.01.024
Abstract: ABSTRACT Previously we established reporter cell lines for human cytomegalovirus (HCMV) and varicella zoster virus (VZV) and identified several antiviral compounds against these viruses using the reporter cells. In this study, we found that one… read more here.
Keywords: vzv ie62; hcmv; thienylcarboxamide derivative; activation ... See more keywords
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Sign Up to like & getrecommendations! Published in 2022 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2022.03.007
Abstract: Viruses are responsible for some of the most deadly human diseases, yet available vaccines and antivirals address only a fraction of the potential viral human pathogens. Here, we provide a methodology for managing human herpesvirus… read more here.
Keywords: protease; catalytic cysteine; hcmv; non catalytic ... See more keywords
Collaborative national multicenter for the identification of conversion factors from copies/mL to international units/mL for the normalization of HCMV DNA load.
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2019.05.012
Abstract: The present multicentric (n = 11 laboratories) study aimed to identify conversion factors from copies/mL to international units (IU)/mL for the normalization of HCMV DNA load using the first WHO International Standard for HCMV nucleic acid amplification… read more here.
Keywords: hcmv dna; factors copies; hcmv; conversion factors ... See more keywords
Human cytomegalovirus utilises cellular dual-specificity tyrosine phosphorylation-regulated kinases during placental replication.
Sign Up to like & getrecommendations! Published in 2018 at "Placenta"
DOI: 10.1016/j.placenta.2018.10.002
Abstract: INTRODUCTION Congenital cytomegalovirus (HCMV) infection may cause significant fetal malformation and in severe cases fetal and neonatal death. Fetal injury may be caused indirectly by the placental response to infection. Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs)… read more here.
Keywords: dual specificity; specificity tyrosine; hcmv; dyrk1a ... See more keywords
Persistent HCMV infection of a glioblastoma cell line contributes to the development of resistance to Temozolomide.
Sign Up to like & getrecommendations! Published in 2019 at "Virus research"
DOI: 10.1016/j.virusres.2019.197829
Abstract: Glioblastoma multiforme (GBM) is the most aggressive form of primary human gliomas. While chemotherapy using the DNA alkylating agent temozolomide (TMZ) is a first line treatment for GBMs, the development of resistance to TMZ is… read more here.
Keywords: cell line; infection; hcmv; resistance ... See more keywords