Temporal dynamics of HCMV gene expression in lytic and latent infections.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110653
Abstract: During productive human cytomegalovirus (HCMV) infection, viral genes are expressed in a coordinated cascade that conventionally relies on the dependencies of viral genes on protein synthesis and viral DNA replication. By contrast, the transcriptional landscape… read more here.
Keywords: gene; gene expression; hcmv gene; lytic latent ... See more keywords
SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011316
Abstract: The presence of human cytomegalovirus (HCMV) in glioblastoma (GBM) and improved outcomes of GBM patients receiving therapies targeting the virus have implicated HCMV in GBM progression. However, a unifying mechanism that accounts for the contribution… read more here.
Keywords: glioma; hcmv gene; gene expression; expression ... See more keywords