Improved Protease-Targeting and Biopharmaceutical Properties of Novel Prodrugs of Ganciclovir.
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DOI: 10.1021/acs.molpharmaceut.7b00792
Abstract: The prodrug strategy has been frequently employed as a chemical approach for overcoming the disadvantages of existing parent drugs. In this report, we synthesized four monoester prodrugs of ganciclovir, an anticytomegalovirus drug, and demonstrated their… read more here.
Keywords: ganciclovir prodrugs; hcmv protease; prodrugs ganciclovir; biopharmaceutical properties ... See more keywords