Deletion of the Na/HCO3 Transporter NBCn1 Protects Hippocampal Neurons from NMDA-induced Seizures and Neurotoxicity in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52413-0
Abstract: The Na/HCO3 cotransporter NBCn1/SLC4A7 can affect glutamate neurotoxicity in primary cultures of rat hippocampal neurons. Here, we examined NMDA-induced neurotoxicity in NBCn1 knockout mice to determine whether a similar effect also occurs in the mouse… read more here.
Keywords: hippocampal neurons; nmda induced; transporter nbcn1; hco3 transporter ... See more keywords
Characterization of human 'AE4' as an electrogenic Na+-coupled HCO3 – transporter
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5735134
Abstract: Human ‘AE4’ (Anion Exchanger 4; GenBank ID: AAK16733) has 84% sequence identity at the amino-acid level to the previously cloned rabbit AE4 (Tsuganezawa et al, JBC 2001 and Parker et al, BBRC 2001). Although rabbit… read more here.
Keywords: hae4; physiology; hco3 transporter; coupled hco3 ... See more keywords