Comparison of platform host cell protein ELISA to process‐specific host cell protein ELISA
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26466
Abstract: During expression of biotherapeutic proteins, complex mixtures of additional proteins are also produced by normal expression machinery of the host cell (termed “host cell proteins,” or HCP). HCPs pose a potential impact to patient safety… read more here.
Keywords: hcp; process; host cell; process specific ... See more keywords
Mass spectrometric evaluation of upstream and downstream process influences on host cell protein patterns in biopharmaceutical products
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Progress"
DOI: 10.1002/btpr.2788
Abstract: For production of different monoclonal antibodies (mAbs), biopharmaceutical companies often use related upstream and downstream manufacturing processes. Such platforms are typically characterized regarding influence of upstream and downstream process (DSP) parameters on critical quality attributes… read more here.
Keywords: upstream downstream; hcp; process; biopharmaceutical products ... See more keywords
Anxa2‐ and Ctsd‐knockout CHO cell lines to diminish the risk of contamination with host cell proteins
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Progress"
DOI: 10.1002/btpr.2820
Abstract: Chinese hamster ovary (CHO) cells have been used as host cells in the production of a range of recombinant therapeutic proteins, including monoclonal antibodies and Fc‐fusion proteins. Host cell proteins (HCP) represent impurities that must… read more here.
Keywords: cell lines; hcp; anxa2 ctsd; host ... See more keywords
Morphology Evolution of Hcp Cobalt Nanoparticles Induced by Ru Promoter
Sign Up to like & getrecommendations! Published in 2020 at "ChemCatChem"
DOI: 10.1002/cctc.201902270
Abstract: The modification of the equilibrium morphology to expose active facets of cobalt nanoparticles is essential for tailoring and controlling its catalytic performance. Periodic density functional theory (DFT) was applied to systematically investigate the structure and… read more here.
Keywords: nanoparticles induced; induced promoter; morphology; cobalt nanoparticles ... See more keywords
Hydroxy-Functionalized Hypercrosslinked Polymers (HCPs) as Dual Phase Radioactive Iodine Scavengers: Synergy of Porosity and Functionality.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202200212
Abstract: Large-scale nuclear power plant production of iodine radionuclides (129 I, 131 I) pose huge threat in the events of nuclear disaster. Effective removal of radioiodine from nuclear waste is one of the most critical challenge… read more here.
Keywords: hcp; hypercrosslinked polymers; hydroxy functionalized; functionalized hypercrosslinked ... See more keywords
[COVID-19 outbreak investigation in a geriatric palliative hospital].
Sign Up to like & getrecommendations! Published in 2021 at "Zeitschrift fur Gerontologie und Geriatrie"
DOI: 10.1007/s00391-021-01930-7
Abstract: BACKGROUND During the second COVID-19 wave, a large COVID-19 outbreak happened at a 90-bed geriatric palliative care hospital in December 2020, whereby 32 % of the healthcare personnel (HCP) and 29 patients became infected within 23 days and 13 patients died. The… read more here.
Keywords: covid outbreak; geriatric palliative; outbreak investigation; hospital ... See more keywords
Salmonella enteritidis Hcp distribute in the cytoplasm and regulate TNF signaling pathway in BHK-21 cells
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02296-0
Abstract: Hemolysin-coregulated protein (Hcp) of Salmonella enteritidis is known to be a structural and effector protein of the T6SS, but little is known about the role of Hcp in host cells. In this study, Hcp was… read more here.
Keywords: tnf signaling; salmonella enteritidis; hcp; signaling pathway ... See more keywords
Photonic thermal control to naturally cool and heat the building
Sign Up to like & getrecommendations! Published in 2018 at "Applied Thermal Engineering"
DOI: 10.1016/j.applthermaleng.2017.12.041
Abstract: Abstract Photon particle has been modeled to be decoded by the curtain wall of the building to create a natural cooling and heating system for a building by implementing the Bose-Einstein (B-E) photon distribution mechanism… read more here.
Keywords: photon; state photon; hcp; building ... See more keywords
The effect of HCP on the formation of twin boundaries and dislocations in Ni–Co alloys
Sign Up to like & getrecommendations! Published in 2021 at "Current Applied Physics"
DOI: 10.1016/j.cap.2021.05.012
Abstract: Abstract In this study, molecular dynamics (MD) was used to simulate the rapid solidification process of Ni47Co53 and Ni48Co52 alloys at a cooling rate of 1012 K/s. The effects of HCP on the formation of twin… read more here.
Keywords: formation twin; hcp; hcp formation; twin boundaries ... See more keywords
Mechanically stable superhydrophobic surface on cement-based materials
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Physics"
DOI: 10.1016/j.chemphys.2020.110912
Abstract: Abstract Superhydrophobic surface is one of the important strategies for the application of water and ice resistance. In this study, we focused on the nano structure of hydration product itself of cement and superhydrophobic surface… read more here.
Keywords: superhydrophobic surface; mechanically stable; surface; hcp ... See more keywords
The competition of densification and structure ordering during crystallization of HCP-Mg in the framework of layering
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2017.04.043
Abstract: Abstract In this paper, we performed an NPT molecular dynamics simulation of crystallization process of HCP-Mg to probe the competition between densification and structural ordering. Two opposite layering patterns, i.e. outward and inward , were… read more here.
Keywords: densification; crystallization; competition densification; structural ordering ... See more keywords