LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "hcp5" as a keyword



Photo by tcwillmott from unsplash

LncRNA HCP5 promotes LAML progression via PSMB8-mediated PI3K/AKT pathway activation

Sign Up to like & get
recommendations! Published in 2019 at "Naunyn-Schmiedeberg's Archives of Pharmacology"

DOI: 10.1007/s00210-019-01788-y

Abstract: Acute myeloid leukemia is an aggressive myeloid malignancy, characterized by rapid cellular proliferation and generally high mortality. Due to the lack of a complete understanding of AML, its clinical outcomes are still not satisfactory. In… read more here.

Keywords: hcp5; pathway activation; pi3k akt; psmb8 ... See more keywords
Photo by nci from unsplash

Overexpression of lncRNA HCP5 in human umbilical cord mesenchymal stem cell-derived exosomes promoted the proliferation and inhibited the apoptosis of ovarian granulosa cells via the musashi RNA-binding protein 2/oestrogen receptor alpha 1 axis.

Sign Up to like & get
recommendations! Published in 2022 at "Endocrine journal"

DOI: 10.1507/endocrj.ej21-0653

Abstract: HCP5 has been reported to be downregulated in ovarian granulosa cells (OGCs) and to facilitate cell proliferation. Human umbilical cord mesenchymal stem cell exosome (hucMSCs-exo) treatment can prevent OGCs apoptosis in vitro. However, the functional… read more here.

Keywords: cell; apoptosis; derived exosomes; proliferation ... See more keywords
Photo by nci from unsplash

HCP5 Promotes Proliferation and Contributes to Cisplatin Resistance in Gastric Cancer Through miR-519d/HMGA1 Axis

Sign Up to like & get
recommendations! Published in 2021 at "Cancer Management and Research"

DOI: 10.2147/cmar.s289997

Abstract: Introduction The long-non-coding RNA HCP5 (HLA complex P5) has been extensively linked to the ability of cancer cells to resist chemotherapeutic interventions. Here, we investigated the role of HCP5 in gastric cancer (GC) which to-date… read more here.

Keywords: 519d hmga1; hcp5; cancer; resistance ... See more keywords

Geniposide inhibits proliferation and induces apoptosis of diffuse large B-cell lymphoma cells by inactivating the HCP5/miR-27b-3p/MET axis

Sign Up to like & get
recommendations! Published in 2020 at "International Journal of Medical Sciences"

DOI: 10.7150/ijms.51329

Abstract: Diffuse large B-cell lymphoma (DLBCL) is commonly treated with R-CHOP, but ~30 to 50% of the patients are poorly responsive to this strategy. Geniposide, an extract from the Gardenia jasminoides Ellis, plays antitumor roles in… read more here.

Keywords: hcp5; dlbcl; apoptosis; dlbcl cells ... See more keywords