Articles with "hcrt system" as a keyword



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Hypocretins (orexins): The ultimate translational neuropeptides

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Published in 2022 at "Journal of Internal Medicine"

DOI: 10.1111/joim.13406

Abstract: The hypocretins (Hcrts), also known as orexins, are two neuropeptides produced exclusively in the lateral hypothalamus. They act on two specific receptors that are widely distributed across the brain and involved in a myriad of… read more here.

Keywords: hcrt; orexins ultimate; hcrt system; hypocretins orexins ... See more keywords

Plasticity of the hypocretinergic/orexinergic system after a chronic treatment with suvorexant in rats. Role of the hypocretinergic/orexinergic receptor 1 as an autoreceptor

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Published in 2022 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2022.1013182

Abstract: The hypothalamic hypocretinergic/orexinergic (Hcrt/Ox) system is involved in many physiological and pathophysiological processes. Malfunction of Hcrt/Ox transmission results in narcolepsy, a sleep disease caused in humans by progressive neurodegeneration of hypothalamic neurons containing Hcrt/Ox. To… read more here.

Keywords: hcrt1 oxa; hypocretinergic orexinergic; hcrt; hcrt system ... See more keywords