Comparing invasive effects of five foodborne bacterial pathogens in human embryonic intestine 407 cells and human ileocecum HCT-8 cells
Sign Up to like & getrecommendations! Published in 2017 at "Asian pacific Journal of Tropical Biomedicine"
DOI: 10.1016/j.apjtb.2017.09.004
Abstract: Abstract Objective To refine the infectious doses of enteric bacterial pathogens in animal assays and vaccine clinical trials by studying the invasion kinetics of five bacterial pathogens with human intestinal cells. Methods Utilizing in vitro cultured… read more here.
Keywords: pathogens human; invasive effects; ileocecum hct; bacterial pathogens ... See more keywords
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer
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DOI: 10.3390/molecules27134040
Abstract: As a typical dibenzylisoquinoline alkaloid, tetrandrine (TET) is clinically used for the treatment of silicosis, inflammatory pulmonary, and cardiovascular diseases in China. Recent investigations have demonstrated the outstanding anticancer activity of this structure, but its… read more here.
Keywords: acid substituted; hct cells; human colorectal; colorectal cancer ... See more keywords
METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma
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DOI: 10.3892/ijo.2022.5396
Abstract: Colorectal cancer (CRC) is one of top five leading causes of cancer-associated mortalities worldwide. 5-Fluorouracil (5-FU) is the first-line chemotherapeutic drug in the treatment of CRC; however, its antineoplastic efficiency is limited due to acquired… read more here.
Keywords: hct cells; crc; resistance; mettl3 ... See more keywords