Synthesis of polyunsaturated fatty boronic esters and their in vitro inhibition to HCT116 cell lines
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.130578
Abstract: Abstract Five polyunsaturated fatty boronic esters (PUFB) were synthesized using a photoinduced decarboxylative borylation reaction from corresponding polyunsaturated fatty acids (PUFA) and in vitro anti-proliferation activity of these molecules on HCT116 cell lines was tested. The… read more here.
Keywords: polyunsaturated fatty; cell lines; hct116 cell; fatty boronic ... See more keywords
USP49-Mediated Histone H2B Deubiquitination Regulates HCT116 Cell Proliferation through MDM2-p53 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00434-21
Abstract: Posttranslational histone modifications play important roles in regulating chromatin structure and transcriptional regulation. Histone H2B monoubiquitination (H2Bub) is an essential regulator for transcriptional elongation and ongoing transcription. ABSTRACT Posttranslational histone modifications play important roles in… read more here.
Keywords: cell proliferation; mdm2; histone h2b; hct116 cell ... See more keywords