Articles with "hcv coinfected" as a keyword



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Immunological recovery in T-cell activation after sustained virologic response among HIV positive and HIV negative chronic Hepatitis C patients

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Published in 2019 at "Hepatology International"

DOI: 10.1007/s12072-019-09941-8

Abstract: BackgroundRapid decreases in activated CD4+ and CD8+ (HLA-DR + and CD38+ co-expressed) T-lymphocytes have been described within 1–2 weeks of initiating direct-acting antiviral (DAA) therapy among chronic Hepatitis C (CHC) patients. However, it is not known whether these changes are maintained… read more here.

Keywords: hiv hcv; hcv; hcv coinfected; daa therapy ... See more keywords
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Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-48592-5

Abstract: The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who achieved… read more here.

Keywords: hcv antibodies; hcv; hiv hcv; neutralizing anti ... See more keywords
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Comparison of methods and characterization of small RNAs from plasma extracellular vesicles of HIV/HCV coinfected patients

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-67935-1

Abstract: Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) hijack the host exosomal machinery as an additional mechanism of infection and evasion of the immune system, modifying the small RNA (smRNA) cargo during infection. We… read more here.

Keywords: extracellular vesicles; hiv hcv; phenol based; isolation ... See more keywords
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Sustained virologic response and changes in liver fibrosis parameters following 12-wk administration of generic sofosbuvir and daclatasvir in HIV/HCV-coinfected patients with HCV genotype 4 infection.

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Published in 2020 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"

DOI: 10.1093/trstmh/trz120

Abstract: BACKGROUND Novel direct-acting antiviral agents have shown great efficacy and tolerability in HCV-monoinfected patients. However, data are lacking regarding their efficacy and safety in HIV/HCV-genotype (GT) 4-coinfected patients. METHODS A single-centre, prospective study including HIV/HCV-GT… read more here.

Keywords: fibrosis; hcv; hiv hcv; hcv coinfected ... See more keywords
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Sofosbuvir-Based Regimens in HIV/HCV Coinfected Patients After Liver Transplantation: Results From the ANRS CO23 CUPILT Study

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Published in 2018 at "Transplantation"

DOI: 10.1097/tp.0000000000001928

Abstract: Background A recurrence of hepatitis C virus (HCV) after liver transplantation affects survival in human immunodeficiency virus (HIV)/HCV coinfected patients. This study assessed the efficacy and safety of sofosbuvir (SOF)-based regimens in HIV/HCV coinfected patients… read more here.

Keywords: hiv hcv; liver transplantation; transplantation; hcv coinfected ... See more keywords
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LBP‐018: Epidemiological analysis of hepatitis C in Pakistan and other Countries: a current update

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Published in 2018 at "Journal of Viral Hepatitis"

DOI: 10.1111/jvh.23_12935

Abstract: the HCV+ monoinfected group we evaluated the assays HCV AgAb (Monolisa TM HCV AgAb ULTRA and Murex HCV AgAb. This analysis showed a specificity of 99.7% for the AgAb test (Monolisa TM HCV AgAb ULTRA… read more here.

Keywords: hcv agab; group; hcv; hiv hcv ... See more keywords
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Baseline Plasma Metabotype Correlates With Direct-Acting Antiviral Therapy Nonresponse for HCV in HIV–HCV Coinfected Patients

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Published in 2022 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2021.748014

Abstract: Introduction: With the advent of direct-acting antiviral (DAA) therapy for HCV, the cure is achieved at similar rates among HIV–HCV coinfected patients as in HCV mono-infected patients. The present study evaluates host plasma metabolites as… read more here.

Keywords: hiv hcv; therapy; hcv; coinfected patients ... See more keywords
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Longitudinal Assessment of Multiple Immunological and Inflammatory Parameters during Successful DAA Therapy in HCV Monoinfected and HIV/HCV Coinfected Subjects

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231911936

Abstract: In the direct-acting antiviral (DAA) era, it is important to understand the immunological changes after HCV eradication in HCV monoinfected (mHCV) and in HIV/HCV coinfected (HIV/HCV) patients. In this study, we analyzed sub-populations of monocytes,… read more here.

Keywords: hiv hcv; hcv monoinfected; hcv patients; therapy ... See more keywords
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Hepatitis C Virus Affects Tuberculosis-Specific T Cells in HIV-Negative Patients

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Published in 2020 at "Viruses"

DOI: 10.3390/v12010101

Abstract: The occurrence of tuberculosis (TB) and hepatitis C virus (HCV) infections in the same patient presents a unique clinical challenge. The impact of HCV infection on the immune response to TB remains poorly investigated in… read more here.

Keywords: response; hcv; tuberculosis; hepatitis virus ... See more keywords
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CCR5+ T-Cells Homed to the Liver Exhibit Inflammatory and Profibrogenic Signatures in Chronic HIV/HCV-Coinfected Patients

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Published in 2021 at "Viruses"

DOI: 10.3390/v13102074

Abstract: Liver fibrosis is accelerated in patients coinfected with hepatitis C virus and human immunodeficiency virus (HIV), compared with HCV monoinfected patients, although the underlying mechanisms are unknown. We hypothesize that T cells expressing the HIV… read more here.

Keywords: ccr5 cells; hiv hcv; ccr5; hcv coinfected ... See more keywords
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DAA-Based Treatment for HIV–HCV-Coinfected Patients: Analysis of Factors of Sustained Virological Response in a Real-Life Study

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Published in 2020 at "Antiviral Therapy"

DOI: 10.3851/imp3353

Abstract: Background The aim of the present study was to evaluate in HIV-infected patients treated with a direct-acting antiviral agent (DAA)-based regimen the variables associated with sustained virological response (SVR) and the trend in biochemical parameters… read more here.

Keywords: hiv; treatment; study; hiv hcv ... See more keywords