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Published in 2019 at "Hepatology International"
DOI: 10.1007/s12072-019-09941-8
Abstract: BackgroundRapid decreases in activated CD4+ and CD8+ (HLA-DR + and CD38+ co-expressed) T-lymphocytes have been described within 1–2 weeks of initiating direct-acting antiviral (DAA) therapy among chronic Hepatitis C (CHC) patients. However, it is not known whether these changes are maintained…
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Keywords:
hiv hcv;
hcv;
hcv coinfected;
daa therapy ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48592-5
Abstract: The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who achieved…
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Keywords:
hcv antibodies;
hcv;
hiv hcv;
neutralizing anti ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-67935-1
Abstract: Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) hijack the host exosomal machinery as an additional mechanism of infection and evasion of the immune system, modifying the small RNA (smRNA) cargo during infection. We…
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Keywords:
extracellular vesicles;
hiv hcv;
phenol based;
isolation ... See more keywords
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Published in 2020 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"
DOI: 10.1093/trstmh/trz120
Abstract: BACKGROUND Novel direct-acting antiviral agents have shown great efficacy and tolerability in HCV-monoinfected patients. However, data are lacking regarding their efficacy and safety in HIV/HCV-genotype (GT) 4-coinfected patients. METHODS A single-centre, prospective study including HIV/HCV-GT…
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Keywords:
fibrosis;
hcv;
hiv hcv;
hcv coinfected ... See more keywords
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Published in 2018 at "Transplantation"
DOI: 10.1097/tp.0000000000001928
Abstract: Background A recurrence of hepatitis C virus (HCV) after liver transplantation affects survival in human immunodeficiency virus (HIV)/HCV coinfected patients. This study assessed the efficacy and safety of sofosbuvir (SOF)-based regimens in HIV/HCV coinfected patients…
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Keywords:
hiv hcv;
liver transplantation;
transplantation;
hcv coinfected ... See more keywords
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Published in 2018 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.23_12935
Abstract: the HCV+ monoinfected group we evaluated the assays HCV AgAb (Monolisa TM HCV AgAb ULTRA and Murex HCV AgAb. This analysis showed a specificity of 99.7% for the AgAb test (Monolisa TM HCV AgAb ULTRA…
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Keywords:
hcv agab;
group;
hcv;
hiv hcv ... See more keywords
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1
Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.748014
Abstract: Introduction: With the advent of direct-acting antiviral (DAA) therapy for HCV, the cure is achieved at similar rates among HIV–HCV coinfected patients as in HCV mono-infected patients. The present study evaluates host plasma metabolites as…
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Keywords:
hiv hcv;
therapy;
hcv;
coinfected patients ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911936
Abstract: In the direct-acting antiviral (DAA) era, it is important to understand the immunological changes after HCV eradication in HCV monoinfected (mHCV) and in HIV/HCV coinfected (HIV/HCV) patients. In this study, we analyzed sub-populations of monocytes,…
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Keywords:
hiv hcv;
hcv monoinfected;
hcv patients;
therapy ... See more keywords
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Published in 2020 at "Viruses"
DOI: 10.3390/v12010101
Abstract: The occurrence of tuberculosis (TB) and hepatitis C virus (HCV) infections in the same patient presents a unique clinical challenge. The impact of HCV infection on the immune response to TB remains poorly investigated in…
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Keywords:
response;
hcv;
tuberculosis;
hepatitis virus ... See more keywords
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Published in 2021 at "Viruses"
DOI: 10.3390/v13102074
Abstract: Liver fibrosis is accelerated in patients coinfected with hepatitis C virus and human immunodeficiency virus (HIV), compared with HCV monoinfected patients, although the underlying mechanisms are unknown. We hypothesize that T cells expressing the HIV…
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Keywords:
ccr5 cells;
hiv hcv;
ccr5;
hcv coinfected ... See more keywords
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Published in 2020 at "Antiviral Therapy"
DOI: 10.3851/imp3353
Abstract: Background The aim of the present study was to evaluate in HIV-infected patients treated with a direct-acting antiviral agent (DAA)-based regimen the variables associated with sustained virological response (SVR) and the trend in biochemical parameters…
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Keywords:
hiv;
treatment;
study;
hiv hcv ... See more keywords