NMR Analysis Suggests Synergy between the RRM2 and the Carboxy-Terminal Segment of Human La Protein in the Recognition and Interaction with HCV IRES
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DOI: 10.3390/ijms24032572
Abstract: The La protein (lupus antigen) is a ubiquitous RNA-binding protein found in all human cells. It is mainly localized in the nucleus, associates with all RNA polymerase III (Pol III) transcripts, as the first factor… read more here.
Keywords: recognition; spectroscopy; terminal; hcv ires ... See more keywords
Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site
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DOI: 10.3390/v15010008
Abstract: Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region. This study shows that… read more here.
Keywords: ptb1 ptb4; binding protein; ires activity; hcv ires ... See more keywords