HCV core antigen plays an important role in the fight against HCV as an alternative to HCV‐RNA detection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23755
Abstract: To discuss the clinical significance of HCV‐cAg testing in the diagnosis, activity determination, and monitoring of therapeutic effectiveness of HCV infection and its advantages compared with HCV‐RNA and anti‐HCV antibodies detection. read more here.
Keywords: core antigen; antigen plays; hcv; hcv rna ... See more keywords
Amino acid substitutions in the hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by all‐oral direct‐acting antiviral regimens
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25047
Abstract: Impact of substitution of aa70 in the core region (Core aa70) in HCV genotype 1b (HCV‐1b) on hepatocarcinogenesis following eradication of HCV RNA by direct‐acting antiviral therapy is not clear. In a retrospective study, 533… read more here.
Keywords: hcv rna; direct acting; acting antiviral; hepatocarcinogenesis ... See more keywords
Detection of HCV genome in peripheral blood mononuclear cells of Iranian seropositive and HCV RNA negative in plasma of patients with beta‐thalassemia major: Occult HCV infection
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25279
Abstract: Beta (β) thalassemia major is a genetic blood disorder with a deficiency in the hemoglobin beta chain, requiring blood transfusion therapy. Multiple blood transfusions increase the risk of transmitting blood‐borne infections. The aim of this… read more here.
Keywords: hcv; thalassemia major; hcv rna; hcv infection ... See more keywords
Laboratory-based testing for hepatitis C infection using dried blood spot samples: A systematic review and meta-analysis of diagnostic accuracy.
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DOI: 10.1002/rmv.2320
Abstract: The use of dried blood spot (DBS) samples can facilitate the implementation of reflex testing by circumventing the need for centrifugation and freezing of venous blood samples. This systematic review assessed the accuracy of using… read more here.
Keywords: hcv rna; hcv; infection; diagnostic accuracy ... See more keywords
Detection of hepatitis C virus (HCV) RNA in the peripheral blood mononuclear cells of HCV-infected patients following sustained virologic response
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-022-00791-7
Abstract: It is unclear whether direct-acting antiviral drugs (DAAs) result in the complete eradication of HCV infection or whether some quantities of the virus may persist after achieving a sustained virologic response (SVR). Aim The aim… read more here.
Keywords: hcv rna; virologic response; rna peripheral; hcv ... See more keywords
Prevalence of occult hepatitis C virus among hemodialysis patients in Tanta university hospitals: a single-center study
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-0897-y
Abstract: Occult hepatitis C virus infection (OCI) is a newly defined type of infection by the chronic hepatitis virus (HCV) distinguished by the existence of HCV RNA in liver tissue and/or peripheral blood mononuclear cells (PBMCs)… read more here.
Keywords: hemodialysis; hcv; hcv rna; hepatitis virus ... See more keywords
HCV Viral Load Greater Than 1000 IU/ml at Time of Virologic Failure in Direct-Acting Antiviral-Treated Patients
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Therapy"
DOI: 10.1007/s12325-021-01647-4
Abstract: One of the remaining barriers to reaching WHO elimination targets of achieving global hepatitis C (HCV) cure is a lack of an established lower limit of detection (LLOD) to confirm cure post-treatment in near-patient technologies.… read more here.
Keywords: expedition; virologic failure; time; hcv rna ... See more keywords
Evaluation of hepatitis C viral RNA persistence in HIV-infected patients with long-term sustained virological response by droplet digital PCR
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48966-9
Abstract: Several studies have reported the persistence of HCV RNA in liver and/or peripheral blood mononuclear cells (PBMCs) in spite of undetectable viremia in patients who have achieved sustained virological response (SVR). This event, defined as… read more here.
Keywords: rna; hcv; hcv rna; patients long ... See more keywords
High Number of Potential Transmitters Revealed in a Population-based Systematic Hepatitis C Virus RNA Screening Among Human Immunodeficiency Virus-infected Men Who Have Sex With Men
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DOI: 10.1093/cid/ciy545
Abstract: Background The proportion of undiagnosed hepatitis C virus (HCV) infections in high-risk populations, such as human immunodeficiency virus (HIV)-infected men who have sex with men (MSM) is unclear. Identification of potential HCV transmitters is important… read more here.
Keywords: human immunodeficiency; hcv; hcv rna; screening among ... See more keywords
Clinical outcomes in persons coinfected with HIV and HCV: Impact of HCV treatment
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/ciz601
Abstract: Hepatitis C (HCV) cure is associated with changes in lipids and inflammatory biomarkers but its impact on clinical endpoints among treated HIV/HCV coinfected persons is unclear. HIV-positive persons from EuroSIDA with known HCV status after… read more here.
Keywords: incidence; treatment; hcv; hcv rna ... See more keywords
Viral Interference Between Dengue Virus and Hepatitis C Virus Infections
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DOI: 10.1093/ofid/ofaa272
Abstract: Abstract Both dengue virus (DENV) and hepatitis C virus (HCV) belong to the Flaviviridae family and could induce hepatitis. We aimed to investigate the interference between them. In total, 515 patients confirmed with dengue fever… read more here.
Keywords: hepatitis; interference; hcv; hcv rna ... See more keywords