Optimal timing of hepatitis C treatment for patients on the liver transplant waiting list
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DOI: 10.1002/hep.28926
Abstract: The availability of oral direct‐acting antivirals has altered the hepatitis C virus (HCV) treatment paradigm for both pre–liver transplant (LT) and post‐LT patients. There is a perceived trade‐off between pre‐LT versus post‐LT treatment of HCV—treatment… read more here.
Keywords: waiting list; treatment; hepatology; liver transplant ... See more keywords
Evaluating the Prevention Benefit of HCV Treatment: Modeling the SToP‐C Treatment as Prevention Study in Prisons
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DOI: 10.1002/hep.32002
Abstract: Between 2014 and 2019, the SToP‐C trial observed a halving in HCV incidence in four Australian prisons following scale‐up of direct‐acting antiviral (DAA) therapy. However, the contribution of HCV treatment to this decline is unclear… read more here.
Keywords: treatment; study; evaluating prevention; prevention ... See more keywords
Provider Perceptions of Hepatitis C Treatment Adherence and Initiation
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DOI: 10.1007/s10620-019-05877-z
Abstract: Background Significant disparities in hepatitis C (HCV) treatment existed in the interferon treatment era, such that patients with mental health and substance use disorders were less likely to be treated. We aimed to evaluate whether… read more here.
Keywords: adherence initiation; provider; treatment; treatment adherence ... See more keywords
Time to HCV Treatment Disfavors Patients Living with HIV/HCV Co-infection: Findings from a Large Urban Tertiary Center
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DOI: 10.1007/s40615-021-01105-5
Abstract: This study aimed to assess time to hepatitis C (HCV) treatment (i.e., the time between the initial clinic visit for HCV evaluation and the HCV treatment start date), to compare clinical characteristics between patients who… read more here.
Keywords: treatment; infection; hiv hcv; time hcv ... See more keywords
Molecular design, synthesis, and biological evaluation of bisamide derivatives as cyclophilin A inhibitors for HCV treatment.
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DOI: 10.1016/j.ejmech.2019.112031
Abstract: Hepatitis C virus (HCV) is a major cause of end-stage liver diseases. Direct-acting antivirals (DAAs), including inhibitors of nonstructural proteins (NS3/4A protease, NS5A, and NS5B polymerase), represent key components of anti-HCV treatment. However, some DAAs… read more here.
Keywords: design synthesis; bisamide derivatives; molecular design; synthesis biological ... See more keywords
Model projections on the impact of HCV treatment in the prevention of HCV transmission among people who inject drugs in Europe.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.10.010
Abstract: BACKGROUND & AIMS Prevention of hepatitis C virus (HCV) transmission among people who inject drugs (PWID) is critical for eliminating HCV in Europe. We estimated the impact of current and scaled-up HCV treatment with and… read more here.
Keywords: prevalence; treatment; hcv transmission; hcv treatment ... See more keywords
‘I’m over the moon!’: patient-perceived outcomes of hepatitis C treatment
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DOI: 10.1071/py20013
Abstract: Understanding patient-perceived outcomes is crucial for assessing the effectiveness and acceptability of hepatitis C virus (HCV) treatment. This study aimed to explore patient-perceived outcomes of receiving direct-acting antivirals (DAAs). This study was a part of… read more here.
Keywords: treatment; perceived outcomes; patient perceived; hcv treatment ... See more keywords
Clinical outcomes in persons coinfected with HIV and HCV: Impact of HCV treatment
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DOI: 10.1093/cid/ciz601
Abstract: Hepatitis C (HCV) cure is associated with changes in lipids and inflammatory biomarkers but its impact on clinical endpoints among treated HIV/HCV coinfected persons is unclear. HIV-positive persons from EuroSIDA with known HCV status after… read more here.
Keywords: incidence; treatment; hcv; hcv rna ... See more keywords
The Impact of Hepatitis C Virus (HCV) Treatment with Direct-Acting (DAA) on the Incidence of Hepatocellular Carcinoma (HCC) in Patients with Advanced Liver Disease
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DOI: 10.1093/ofid/ofx163.389
Abstract: Abstract Background Use DAA has resulted in widespread eradication of Hepatitis C virus (HCV) infection in patients with advanced liver disease (ALD) compared with interferon (IFN)-based treatment era therapy. Recent reports have indicated an increased… read more here.
Keywords: incidence; hcc; treatment; hcv patients ... See more keywords
2207. Barriers to HCV Treatment in a Safety-Net Hospital System
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DOI: 10.1093/ofid/ofy210.1860
Abstract: Abstract Background In 2016, we implemented a hepatitis C (HCV) screening program for baby boomers (BB) born between 1945 and 1965) using a best practice alert (BPA) in the electronic medical record and patient navigation… read more here.
Keywords: treatment; net hospital; hcv treatment; safety net ... See more keywords
HCV knowledge and Recent Diagnosis Affect HCV Treatment Willingness in Persons Living with HIV.
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DOI: 10.1097/qai.0000000000002643
Abstract: BACKGROUND We assessed the impact of health literacy and hepatitis C (HCV) knowledge on HCV treatment willingness among people living with HIV (PLWH) at an academic HIV clinic. METHODS Cross-sectional analysis of PLWH co-infected with… read more here.
Keywords: health; hcv; hcv knowledge; knowledge ... See more keywords