A Review of kidney transplantation from HCV-Viremic Donors into Negative Recipients.
Sign Up to like & getrecommendations! Published in 2021 at "Kidney international"
DOI: 10.1016/j.kint.2021.06.034
Abstract: The safety and efficacy of direct acting antiviral therapies have allowed the transplantation of organs from hepatitis C virus (HCV)-viremic donors into uninfected recipients. This novel strategy contrasts with the previous standard-of-care practice of limiting… read more here.
Keywords: transplantation hcv; kidney; hcv viremic; viremic donors ... See more keywords
Decision-making Among Hepatitis C Virus-negative Transplant Candidates Offered Organs from Donors with HCV Infection
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DOI: 10.1097/txd.0000000000001341
Abstract: Background. Historically, many organs from deceased donors with hepatitis C virus (HCV) were discarded. The advent of highly curative direct-acting antiviral (DAA) therapies motivated transplant centers to conduct trials of transplanting HCV-viremic organs (nucleic acid… read more here.
Keywords: hcv viremic; hepatitis virus; decision making; decision ... See more keywords
Cost‐effectiveness of using hepatitis C viremic hearts for transplantation into HCV‐negative recipients
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DOI: 10.1111/ajt.16245
Abstract: Outcomes following hepatitis C virus (HCV)‐viremic heart transplantation into HCV‐negative recipients with HCV treatment are good. We assessed cost‐effectiveness between cohorts of transplant recipients willing and unwilling to receive HCV‐viremic hearts. Markov model simulated long‐term… read more here.
Keywords: viremic hearts; transplantation hcv; hcv negative; cost ... See more keywords
Early initiation of glecaprevir/pibrentasvir after transplantation of HCV‐viremic kidneys into HCV‐negative recipients is associated with normalization in the altered inflammatory milieu
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Transplantation"
DOI: 10.1111/ctr.14926
Abstract: Our previous Multicenter Trial to Transplant HCV‐infected Kidneys (MYTHIC) observed that 100% of hepatitis C virus (HCV)‐uninfected patients who received a kidney from an HCV‐infected deceased donor were cured of HCV with an 8‐week regimen… read more here.
Keywords: glecaprevir pibrentasvir; inflammatory milieu; hcv viremic; hcv ... See more keywords
National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2019050462
Abstract: BACKGROUND Recent pilot trials have demonstrated the safety of transplanting HCV-viremic kidneys into HCV-seronegative recipients. However, it remains unclear if allograft function is impacted by donor HCV-viremia or recipient HCV-serostatus. METHODS We used national United… read more here.
Keywords: hcv seronegative; hcv viremic; viremic kidneys; year ... See more keywords
The impact of hepatitis C viremic donor lung allograft characteristics on post-transplantation outcomes.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of cardiothoracic surgery"
DOI: 10.21037/acs.2020.01.03
Abstract: Background There is a low utilization rate of donated donor lungs. Historically, transplantation of lungs from hepatitis C-viremic donors to hepatitis C (HCV) negative recipients was avoided due to concern for worse graft survival. In… read more here.
Keywords: hcv negative; allograft; donor; hcv viremic ... See more keywords