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Combined Inhibition of HDAC and EGFR Reduces Viability and Proliferation and Enhances STAT3 mRNA Expression in Glioblastoma Cells

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Published in 2019 at "Journal of Molecular Neuroscience"

DOI: 10.1007/s12031-019-01280-5

Abstract: Changes in expression of histone deacetylases (HDACs), which epigenetically regulate chromatin structure, and mutations and amplifications of the EGFR gene, which codes for the epidermal growth factor receptor (EGFR), have been reported in glioblastoma (GBM),… read more here.

Keywords: egfr; combined inhibition; viability; inhibition ... See more keywords