Development of New Inhibitors of HDAC1-3 Enzymes Aided by In Silico Design Strategies
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DOI: 10.1021/acs.jcim.1c01557
Abstract: Histone deacetylases (HDACs) are overexpressed in cancer, and their inhibition shows promising results in cancer therapy. In particular, selective class I HDAC inhibitors such as entinostat are proposed to be more beneficial in breast cancer… read more here.
Keywords: development new; hdac inhibitors; hdac1 enzymes; design ... See more keywords