Downregulation of HDAC2 and HDAC3 via oleuropein as a potent prevention and therapeutic agent in MCF‐7 breast cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28193
Abstract: Breast cancer is the most common malignancy in the world with the highest rate of morbidity and mortality. Due to the several side effects of chemotherapy and radiotherapy, recent studies have focused on the use… read more here.
Keywords: cancer; hdac2 hdac3; breast cancer;
The Multifunctional Protein PACS-1 is Required for HDAC2 and HDAC3 Dependent Chromatin Maturation and Genomic Stability
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-1167-x
Abstract: Phosphofurin acidic cluster sorting protein-1 (PACS-1) is a multifunctional membrane traffic regulator that plays important roles in organ homeostasis and disease. In this study, we elucidate a novel nuclear function for PACS-1 in maintaining chromosomal… read more here.
Keywords: chromatin maturation; protein pacs; hdac3; hdac2 hdac3 ... See more keywords
Clinicopathological features and prediction values of HDAC1, HDAC2, HDAC3, and HDAC11 in classical Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2018 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000610
Abstract: Histone deacetylases (HDACs) are involved in multiple physical and pathological processes in classical Hodgkin lymphoma (cHL). The prognostic value of HDACs in cHL patients has not been discussed. The aim of the current study is… read more here.
Keywords: hdac3 hdac11; expression; hdac11; hdac2 hdac3 ... See more keywords
Mitotic H3K9ac is controlled by phase-specific activity of HDAC2, HDAC3, and SIRT1
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.26508/lsa.202201433
Abstract: Combination of immunofluorescence, Western blot, and ChIP-seq revealed the interplay between HDAC2, HDAC3, and SIRT1 in H3K9 deacetylation during mitosis of mammalian cells. Histone acetylation levels are reduced during mitosis. To study the mitotic regulation… read more here.
Keywords: hdac2 hdac3; hdac3; hdac3 sirt1; h3k9ac ... See more keywords