Mdm2 is required for HDAC3 monoubiquitination and stability.
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DOI: 10.1016/j.bbrc.2019.07.052
Abstract: HDAC3, one of the class I histone deacetylase modulates epigenetic landscape through histone modification. HDAC3 also interacts with non-histone proteins including p53 for deacetylation. Moreover, HDAC3 serves as a transcriptional repressor, interacting with NCor1/SMRT complex.… read more here.
Keywords: mdm2; monoubiquitination stability; hdac3 monoubiquitination;