HDAC4 mutant represses chondrocyte hypertrophy by locating in the nucleus and attenuates disease progression of posttraumatic osteoarthritis
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DOI: 10.1186/s12891-021-04947-6
Abstract: Background The aim of this study was to evaluate whether histone deacetylase 4 S246/467/632A mutant (m-HDAC4) has enhanced function at histone deacetylase 4 (HDAC4) to attenuate cartilage degeneration in a rat model of osteoarthritis (OA). Methods… read more here.
Keywords: treated hdac4; hdac4 gfp; hdac4 group; hdac4 ... See more keywords