A multiple sclerosis–protective coding variant reveals an essential role for HDAC7 in regulatory T cells
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abl3651
Abstract: Genome-wide association studies identifying hundreds of susceptibility loci for autoimmune diseases indicate that genes active in immune cells predominantly mediate risk. However, identification and functional characterization of causal variants remain challenging. Here, we focused on… read more here.
Keywords: role; hdac7; variant; hdac7 r166h ... See more keywords