HDAC9 linked to aortic calcification
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-019-0308-9
Abstract: A new study identifies the genetic locus encoding the histone deacetylase HDAC9 as a risk locus associated with calcification of the abdominal aorta and reveals that HDAC9 promotes the development of vascular calcification by modulating… read more here.
Keywords: hdac9 linked; cardiology; linked aortic; calcification ... See more keywords
An HDAC9-associated immune-related signature predicts bladder cancer prognosis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0264527
Abstract: Background The close relationship between histone deacetylase 9 (HDAC9) and immunity has attracted attention. We constructed an immune signature for HDAC9, a vital epigenetic modification, to predict the survival status and treatment benefits in bladder… read more here.
Keywords: prognosis; signature; immune related; risk ... See more keywords
Knockdown of HDAC9 attenuates sepsis-induced myocardial injury and inflammatory response.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental animals"
DOI: 10.1538/expanim.22-0072
Abstract: Myocardial cell damage is associated with apoptosis and excessive inflammatory response in sepsis. Histone deacetylases (HDACs) are implicated in the progression of heart diseases. This study aims to explore the role of histone deacetylase 9… read more here.
Keywords: sepsis; myocardial injury; inflammatory response; hdac9 ... See more keywords
Knockdown of HDAC9 Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Partially by Suppressing the MAPK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s361008
Abstract: Background Histone deacetylase 9 (HDAC9) is a member of the HDAC gene family that plays essential roles in the organization of transcriptional regulation by catalyzing deacetylation of histone proteins. However, the effects of HDAC9 on… read more here.
Keywords: hdac9 knockdown; signaling pathway; mapk signaling; osteogenic differentiation ... See more keywords
circ_0003204 Regulates Cell Growth, Oxidative Stress, and Inflammation in ox-LDL-Induced Vascular Endothelial Cells via Regulating miR-942-5p/HDAC9 Axis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.646832
Abstract: Background: Atherosclerosis (AS) is a typical inflammatory vascular disease. Many reports corroborated that circular RNAs (circRNAs) is involved in AS progression. However, the potential function and possible mechanism of circ_0003204 in AS progression remain indistinct.… read more here.
Keywords: mir 942; stress inflammation; ldl; hdac9 ... See more keywords
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.703632
Abstract: The Mads/Mef2 (Mef2a/b/c/d) family of transcription factors (TFs) regulates differentiation of muscle cells, neurons and hematopoietic cells. By functioning in physiological feedback loops, Mef2 TFs promote the transcription of their repressor, Hdac9, thereby providing temporal… read more here.
Keywords: mef2d; mef2c; foxp3 regulatory; hdac9 ... See more keywords
MicroRNA-936 inhibits the malignant phenotype of retinoblastoma by directly targeting HDAC9 and deactivating the PI3K/AKT pathway
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Reports"
DOI: 10.3892/or.2020.7456
Abstract: MicroRNA-936 (miR-936) has been reported to play important roles in the progression of non-small cell lung cancer and glioma. However, the expression and functions of miR-936 in retinoblastoma (RB) remain elusive and need to be… read more here.
Keywords: microrna 936; pi3k akt; hdac9; expression ... See more keywords