Human DBR1 modulates the recycling of snRNPs to affect alternative RNA splicing and contributes to the suppression of cancer development
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DOI: 10.1038/onc.2017.150
Abstract: The contribution of RNA processing to tumorigenesis is understudied. Here, we report that the human RNA debranching enzyme (hDBR1), when inappropriately regulated, induces oncogenesis by causing RNA processing defects, for example, splicing defects. We found… read more here.
Keywords: hdbr1; human dbr1; rna; expression ... See more keywords