Association Between High-Density Lipoprotein Cholesterol Levels and Adverse Cardiovascular Outcomes in High-risk Populations.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.0912
Abstract: Importance Previous studies have shown lower cardiovascular risk with higher high-density lipoprotein cholesterol (HDL-C) levels. However, recent data in the general population have shown increased risk of adverse outcomes at very high HDL-C concentrations. Objective… read more here.
Keywords: high hdl; risk; hdl levels; association ... See more keywords
HDL and type 2 diabetes: the chicken or the egg?
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-021-05509-0
Abstract: HDL is a complex macromolecular cluster of various components, such as apolipoproteins, enzymes and lipids. Quality evidence from clinical and epidemiological studies led to the principle that HDL-cholesterol (HDL-C) levels are inversely correlated with the… read more here.
Keywords: hdl functionality; hdl levels; type diabetes; hdl ... See more keywords
Serum C-peptide as a key contributor to lipid-related residual cardiovascular risk in the elderly.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of gerontology and geriatrics"
DOI: 10.1016/j.archger.2017.05.018
Abstract: OBJECTIVES The serum levels of C-peptide, an important risk factor for cardiovascular disease (CVD), increase with age. This study aimed to investigate the association between serum C-peptide and increased risk for CVD with altered lipid… read more here.
Keywords: hdl levels; risk; serum; serum peptide ... See more keywords
Non-HDL-C levels and residual cardiovascular risk: Do population-specific precision approaches offer advantages?
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.05.010
Abstract: Since the initial discovery of the links between dietary fats, blood lipids and coronary heart disease (CHD) risks nearly eight decades ago [1, 2], extensive research has been conducted in this area and the risk… read more here.
Keywords: hdl levels; risk; non hdl; population specific ... See more keywords
Risk factors: HDL-C levels not specific to cardiovascular mortality
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Cardiology"
DOI: 10.1038/nrcardio.2016.186
Abstract: Individuals with low (≤30 mg/dl) levels of high-density lipoprotein cholesterol (HDL-C), have higher cardiovascular and noncardiovascular mortality than individuals with intermediate levels of HDL-C. However, individuals with high levels of HDL-C (>70 mg/dl in men;… read more here.
Keywords: hdl levels; risk; risk factors; mortality ... See more keywords
Dyslipidaemia: Is CETP inhibition a viable therapeutic strategy?
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Cardiology"
DOI: 10.1038/nrcardio.2017.87
Abstract: LDL The rationale for targeting cholesteryl ester transfer protein (CETP), an enzyme that promotes the transfer of cholesteryl esters from HDL to very low-density lipoprotein and LDL, to reduce the risk of cardiovascular disease is… read more here.
Keywords: hdl levels; trial; disease; cetp inhibition ... See more keywords
Urinary albumin creatinine ratio is associated with lipid profile
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-65037-w
Abstract: Moderately elevated albuminuria (30–300 mg/g) is a marker of renal dysfunction and a risk factor of cardiovascular disease. Additionally, several recent studies have reported a relationship between moderately elevated albuminuria and triglyceride (TG) levels. Therefore,… read more here.
Keywords: moderately elevated; hdl; elevated albuminuria; creatinine ratio ... See more keywords
The change of paradigm: high HDL-c levels could not mean a long lifespan
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.2739
Abstract: It is known that a low HDL-c level is associated with a high risk of overall mortality. Consequently, it was presumed that achieving higher levels of high-density lipoprotein cholesterol (HDL-c) would reduce the risk or… read more here.
Keywords: overall mortality; hdl; risk; high hdl ... See more keywords
Clinical Deep Data Accumulation System (CLIDAS) reveals a "Lipid paradox" of hypertriglyceridemia in Japanese patients
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.2825
Abstract: The association between triglycerides (TG), HDL cholesterol (HDL-C) and the prognosis of cardiovascular disease has not been established. The aim of this study was to elucidate the relationships between the combination of TG and HDL-C… read more here.
Keywords: low hdl; hdl; high hdl; group ... See more keywords
High-density lipoprotein (HDL) and infections: a versatile culprit
Sign Up to like & getrecommendations! Published in 2018 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehx734
Abstract: For several years, HDL has been referred to as ‘good cholesterol’, exerting a plethora of beneficial effects mainly on cells of the vascular tree. HDL prevents endothelial dysfunction, reduces proinflammatory cell activation, and promotes reverse… read more here.
Keywords: hdl levels; disease; cholesterol; hdl ... See more keywords
Impact of phase ii exercise-based cardiac rehabilitation on HDL-c levels and the predictive role of systemic inflammatory index in patients with coronary artery disease
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwaf236.339
Abstract: High-density lipoprotein cholesterol (HDL-C) and Cardiac Rehabilitation (CR) are both established beneficial factors in managing patients with Coronary Artery Disease (CAD). Despite numerous attempts to manipulate serum HDL-C levels, CR's impact on HDL-C levels requires… read more here.
Keywords: rehabilitation; hdl; exercise based; phase ... See more keywords