Association Between High-Density Lipoprotein Cholesterol Levels and Adverse Cardiovascular Outcomes in High-risk Populations.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.0912
Abstract: Importance Previous studies have shown lower cardiovascular risk with higher high-density lipoprotein cholesterol (HDL-C) levels. However, recent data in the general population have shown increased risk of adverse outcomes at very high HDL-C concentrations. Objective… read more here.
Keywords: high hdl; risk; hdl levels; association ... See more keywords
HDL and type 2 diabetes: the chicken or the egg?
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-021-05509-0
Abstract: HDL is a complex macromolecular cluster of various components, such as apolipoproteins, enzymes and lipids. Quality evidence from clinical and epidemiological studies led to the principle that HDL-cholesterol (HDL-C) levels are inversely correlated with the… read more here.
Keywords: hdl functionality; hdl levels; type diabetes; hdl ... See more keywords
Serum C-peptide as a key contributor to lipid-related residual cardiovascular risk in the elderly.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of gerontology and geriatrics"
DOI: 10.1016/j.archger.2017.05.018
Abstract: OBJECTIVES The serum levels of C-peptide, an important risk factor for cardiovascular disease (CVD), increase with age. This study aimed to investigate the association between serum C-peptide and increased risk for CVD with altered lipid… read more here.
Keywords: hdl levels; risk; serum; serum peptide ... See more keywords
Non-HDL-C levels and residual cardiovascular risk: Do population-specific precision approaches offer advantages?
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.05.010
Abstract: Since the initial discovery of the links between dietary fats, blood lipids and coronary heart disease (CHD) risks nearly eight decades ago [1, 2], extensive research has been conducted in this area and the risk… read more here.
Keywords: hdl levels; risk; non hdl; population specific ... See more keywords
Risk factors: HDL-C levels not specific to cardiovascular mortality
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Cardiology"
DOI: 10.1038/nrcardio.2016.186
Abstract: Individuals with low (≤30 mg/dl) levels of high-density lipoprotein cholesterol (HDL-C), have higher cardiovascular and noncardiovascular mortality than individuals with intermediate levels of HDL-C. However, individuals with high levels of HDL-C (>70 mg/dl in men;… read more here.
Keywords: hdl levels; risk; risk factors; mortality ... See more keywords
Dyslipidaemia: Is CETP inhibition a viable therapeutic strategy?
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Cardiology"
DOI: 10.1038/nrcardio.2017.87
Abstract: LDL The rationale for targeting cholesteryl ester transfer protein (CETP), an enzyme that promotes the transfer of cholesteryl esters from HDL to very low-density lipoprotein and LDL, to reduce the risk of cardiovascular disease is… read more here.
Keywords: hdl levels; trial; disease; cetp inhibition ... See more keywords
High-density lipoprotein (HDL) and infections: a versatile culprit
Sign Up to like & getrecommendations! Published in 2018 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehx734
Abstract: For several years, HDL has been referred to as ‘good cholesterol’, exerting a plethora of beneficial effects mainly on cells of the vascular tree. HDL prevents endothelial dysfunction, reduces proinflammatory cell activation, and promotes reverse… read more here.
Keywords: hdl levels; disease; cholesterol; hdl ... See more keywords
P528 Lipid metabolism, insülin resistance and NAFLD in obesity
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-epa.863
Abstract: Obesity, insülin resistance (IR) and non-alcoholic fatty liver disease (NAFLD) are the major components of the metabolic syndrome. On the other hand, it is known that primer hypolipidemia is associated with increased prevalence of NAFLD.… read more here.
Keywords: hdl levels; lin resistance; ins lin; obesity ... See more keywords
The Late-Gestational Triglyceride to High-Density Lipoprotein Cholesterol Ratio Is Associated with Neonatal Macrosomia in Women without Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Endocrinology"
DOI: 10.1155/2020/7250287
Abstract: Objective To investigate the associations between late-gestational dyslipidemia, expressed as the ratio between triglycerides (TGs) and high-density lipoprotein cholesterol (HDL), and the risk of macrosomia among nondiabetic pregnant women. Methods In this case-control study, 171… read more here.
Keywords: hdl levels; associated neonatal; ratio; hdl ... See more keywords
Mediterranean Approach to Improving High-Density Lipoprotein Function
Sign Up to like & getrecommendations! Published in 2017 at "Circulation"
DOI: 10.1161/circulationaha.117.026278
Abstract: Article, see p 633 The complex interrelationships among diet, high-density lipoprotein (HDL), and cardiovascular risk have been a topic of great interest for decades.1 HDL cholesterol (HDL-C) levels are strongly inversely associated with cardiovascular disease… read more here.
Keywords: hdl levels; risk; high density; hdl ... See more keywords
Increasing high-density lipoprotein cholesterol levels for cardiovascular benefit: The end of a dream?
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Preventive Cardiology"
DOI: 10.1177/2047487318820976
Abstract: For many decades, epidemiological studies have supported an inverse relationship between high-density lipoprotein cholesterol (HDL-C) levels and the risk of cardiovascular disease. This led to focus the efforts not only on the development of lipid-lowering… read more here.
Keywords: hdl levels; risk; density lipoprotein; lipoprotein cholesterol ... See more keywords