Both living and dead Faecalibacterium prausnitzii alleviate HDM-induced allergic asthma through the modulation of gut microbiota and short-chain fatty acid (SCFAs) production.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11207
Abstract: BACKGROUND Asthma is increasingly prevalent worldwide, and novel strategies to prevent or treat this disease are needed. Probiotic intervention has recently been reported to be effective for asthma prevention. Here, we explored the effects of… read more here.
Keywords: living dead; hdm induced; scfas production; prausnitzii ... See more keywords
Implication of NOD-1 receptor in house dust mite (HDM)-induced asthma
Sign Up to like & getrecommendations! Published in 2021 at "Revue Des Maladies Respiratoires"
DOI: 10.1016/j.rmr.2021.02.013
Abstract: Introduction NOD1 is an innate pattern-recognition sensor for Gram-negative peptidoglycan (PG) that is involved in the development of allergic asthma and signals through the kinase RIPK2. The aim of this study was to investigate the role… read more here.
Keywords: nod receptor; asthma; hdm induced; hdm ... See more keywords
Vagal C-fibers mediate HDM induced airway hyperreactivity via PAR1 receptors
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5734190
Abstract: Airway hyperreactivity (AHR) is a hallmark of allergic asthma, and the major cause of exacerbations. Although acute bronchospasm can be mitigated by bronchodilators and corticosteroids, no therapeutics effectively target AHR. Recent studies have shown that… read more here.
Keywords: airway hyperreactivity; hdm; physiology; mice ... See more keywords
Reprogramming alternative macrophage polarization by GATM-mediated endogenous creatine synthesis: A potential target for HDM-induced asthma treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.937331
Abstract: Cellular energy metabolism plays a crucial role in the regulation of macrophage polarization and in the execution of immune functions. A recent study showed that Slc6a8-mediated creatine uptake from exogenous supplementation modulates macrophage polarization, yet… read more here.
Keywords: gatm; macrophage polarization; creatine synthesis; polarization ... See more keywords