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   Articles with "hdmtx" as a keyword



P14.118 Carboxypeptidase G2 (CPG2) rescue after high dose methotrexate (hdMTX) chemotherapy for Primary CNS Lymphoma (PCNSL). A French LOC network study

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recommendations! Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noz126.353

Abstract: CPG2 is an efficient rescue recombinant bacterial enzyme that cleaves MTX into inactive metabolites. As hdMTX is the key agent in PCNSL, delayed MTX excretion (DME), and/or MTX induced nephrotoxicity (MIN) may expose the patients… read more here.

Keywords: loc network; cpg2; study; rescue ... See more keywords
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The Application of 99mTc-DTPA Renal Dynamic Imaging to Measuring Renal Function of Children with Acute Lymphoblastic Leukemia after Induction Therapy

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recommendations! Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/3687134

Abstract: Purpose The study was aimed at assessing renal functions of children with acute lymphoblastic leukemia (ALL) after induction therapy by 99mTc-DTPA renal dynamic imaging Gates method (GFRGates) and investigating whether renal function after induction therapy… read more here.

Keywords: hdmtx induced; renal function; induction therapy; hdmtx ... See more keywords
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Is hypoalbuminemia a risk factor for high-dose methotrexate toxicity in children with acute lymphoblastic leukemia?

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recommendations! Published in 2022 at "Journal of the Egyptian National Cancer Institute"

DOI: 10.1186/s43046-022-00122-7

Abstract: Repeated high-dose methotrexate (HDMTX) is a critical component of contemporary childhood acute lymphoblastic leukemia (ALL) treatment regimens. Serum albumin is considered a carrier of methotrexate (MTX) in the blood. Hypoalbuminemia is not a rare finding… read more here.

Keywords: hdmtx; infusion; serum albumin; risk ... See more keywords
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A Systematic Review of High-Dose Methotrexate for Adults with Primary Central Nervous System Lymphoma

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recommendations! Published in 2023 at "Cancers"

DOI: 10.3390/cancers15051459

Abstract: Simple Summary High-dose methotrexate (HDMTX) is the backbone of induction therapy for primary central nervous system lymphoma (PCNSL). There are numerous different protocols to treat PCNSL that incorporate a wide range of HDMTX doses and… read more here.

Keywords: hdmtx; primary central; central nervous; dose methotrexate ... See more keywords