Sign Up to like & get
recommendations!
0
Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20191914
Abstract: Abstract Precise genome editing with directed base insertion or targeted point mutations can be achieved by CRISPR/Cas9-mediated homology-directed repair (HDR) and is of great significance in clinical disease therapy. However, HDR efficiency, compared with non-homologous…
read more here.
Keywords:
sarcoma associated;
kaposi sarcoma;
associated herpesvirus;
directed repair ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2204259119
Abstract: CRISPR-associated (Cas) enzymes have revolutionized biology by enabling RNA-guided genome editing. Homology-directed repair (HDR) in the presence of donor templates is currently the most versatile method to introduce precise edits following CRISPR-Cas-induced double-stranded DNA cuts,…
read more here.
Keywords:
genome editing;
repair;
crispr;
hdr efficiency ... See more keywords