In schizophrenia, immune-inflammatory pathways are strongly associated with depressive and anxiety symptoms, which are part of a latent trait which comprises neurocognitive impairments and schizophrenia symptoms.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2021.03.062
Abstract: BACKGROUND The aim is to examine whether biomarkers of the immune-inflammatory response (IRS) and endogenous opioid (EOS) systems are associated with affective symptoms in schizophrenia. METHODS We recruited 115 schizophrenia patients and 43 healthy controls… read more here.
Keywords: schizophrenia; hdrs; strongly associated; schizophrenia symptoms ... See more keywords
Do not blame the SSRIs: blame the Hamilton Depression Rating Scale
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropsychiatrica"
DOI: 10.1017/neu.2017.6
Abstract: Dear Editor, In their recent paper entitled ‘Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis’ (1), Jakobsen et al. conclude that ‘The… read more here.
Keywords: depression; total score; jakobsen; analysis ... See more keywords
The association of ARRB1 polymorphisms with response to antidepressant treatment in depressed patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.974570
Abstract: Introduction: β-arrestin 1, a protein encoded by ARRB1 involved in receptor signaling, is a potential biomarker for the response to antidepressant drug (ATD) treatment in depression. We examined ARRB1 genetic variants for their association with… read more here.
Keywords: depressed patients; response antidepressant; treatment depressed; treatment ... See more keywords