A novel quantitative microarray antibody capture assay identifies an extremely high hepatitis delta virus prevalence among hepatitis B virus–infected mongolians
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28957
Abstract: Hepatitis delta virus (HDV) causes the most severe form of human viral hepatitis. HDV requires a hepatitis B virus (HBV) coinfection to provide HDV with HBV surface antigen envelope proteins. The net effect of HDV… read more here.
Keywords: antibody; hbv; prevalence; hdv ... See more keywords
Lonafarnib—A new member of the Delta Force?
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32435
Abstract: Chronic HDV requires the envelope (HBsAg) of HBV to enter the hepatocyte, spread intrahepatically, and disseminate. Chronic HDV is the most severe form of viral hepatitis. The risk of HCC and liver cirrhosis associated with… read more here.
Keywords: chronic hdv; therapy; hdv; hepatitis ... See more keywords
Evolution of HBV S-gene in the backdrop of HDV co-infection.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medical virology"
DOI: 10.1002/jmv.25092
Abstract: BACKGROUND HBV-HDV co-infected people have a higher chance of developing cirrhosis, fulminant hepatitis, and hepatocellular carcinoma (HCC) compared to those infected only with HBV. OBJECTIVE The present study was conducted to investigate HBV genotypes and… read more here.
Keywords: hbv gene; hbv; infected patients; hdv ... See more keywords
Hepatitis D infection in Brazil: Prevalence and geographical distribution of anti‐Delta antibody
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25196
Abstract: In Brazil, the Amazon Basin is endemic for hepatitis D virus (HDV) infection; however, studies in other regions of the country are scarce. This study aims to map the seroepidemiological situation of anti‐Delta antibodies in… read more here.
Keywords: delta antibodies; hepatitis; infection; prevalence ... See more keywords
First molecular epidemiological study of hepatitis B and D in individuals infected with human T‐lymphotropic virus 1/2 from Argentina
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DOI: 10.1002/jmv.26366
Abstract: Human T‐lymphotropic virus 1/2 (HTLV‐1/2), hepatitis B virus (HBV), and hepatitis D virus (HDV) share transmission routes. Argentina shows low prevalence of HTLV‐1/2, HBV, and HDV infections; however, this situation may vary according to the… read more here.
Keywords: hepatitis; hbv; prevalence; study ... See more keywords
Entry Inhibitors of Hepatitis B and D Viruses.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-16-8702-0_12
Abstract: Human hepatitis B virus (HBV) and hepatitis D virus (HDV) cause acute and chronic infections. The latter poses a serious public health threat as it is the major cause of chronic hepatitis, liver failure, cirrhosis,… read more here.
Keywords: hbv; inhibitors hepatitis; entry inhibitors; hdv ... See more keywords
Molecular characterization of the full-length genome sequences of HDV strains circulating in Tunisia
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Virology"
DOI: 10.1007/s00705-018-3790-1
Abstract: While Tunisia is endemic for hepatitis B virus (HBV), a recent large-scale retrospective study, revealed a very low prevalence (2%) of hepatitis Delta virus (HDV) (Yacoubi et al. in J Clin Virol 72:126–132, 2015). All… read more here.
Keywords: full length; tunisia; hdv; genome ... See more keywords
A Brief Update on the Management of Hepatitis Delta
Sign Up to like & getrecommendations! Published in 2018 at "Current Gastroenterology Reports"
DOI: 10.1007/s11894-018-0666-1
Abstract: Hepatitis delta (HDV) is an incomplete virus requiring hepatitis B (HBV), specifically hepatitis B surface antigen (HBsAg) to replicate. HDV can present as an acute or chronic infection and has been described as the most… read more here.
Keywords: hepatitis delta; hepatitis; brief update; update management ... See more keywords
A screening assay for the identification of host cell requirements and antiviral targets for hepatitis D virus infection
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DOI: 10.1016/j.antiviral.2017.02.008
Abstract: ABSTRACT Hepatitis delta virus (HDV) is a minimalistic satellite virus of hepatitis B virus (HBV). HBV/HDV co‐infection, i.e. “hepatitis D”, is the most severe form of viral hepatitis. No effective therapy for HDV infection is… read more here.
Keywords: hepatitis virus; hdv infection; infection; hdv ... See more keywords
Down-regulation of hepatitis delta virus super-infection in the woodchuck model.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2019.03.002
Abstract: Mechanisms mediating clearance of hepatitis delta virus (HDV) are poorly understood. This study analyzed in detail profound down-regulation of HDV infection in the woodchuck model. Super-infection with HDV of woodchucks chronically infected with HBV-related woodchuck… read more here.
Keywords: hepatitis delta; hepatitis; infection; infectivity ... See more keywords
Recapitulation of HDV infection in a fully permissive hepatoma cell line allows efficient drug evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10211-2
Abstract: Hepatitis delta virus (HDV) depends on the helper function of hepatitis B virus (HBV), which provides the envelope proteins for progeny virus secretion. Current infection-competent cell culture models do not support assembly and secretion of… read more here.
Keywords: cell line; secretion; infection; hdv ... See more keywords