Deciphering Binding Interactions of IL-23R with HDX-MS: Mapping Protein and Macrocyclic Dodecapeptide Ligands.
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DOI: 10.1021/acsmedchemlett.8b00255
Abstract: Molecular characterization of the binding epitope of IL-23R and its cognate cytokine IL-23 is paramount to understand the role in autoimmune diseases and to support the discovery of new inhibitors of this protein-protein interaction. Our… read more here.
Keywords: interactions 23r; hdx mapping; 23r hdx; deciphering binding ... See more keywords