Two-photon calcium imaging of seizures in awake, head-fixed mice.
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102380
Abstract: Epilepsy is a severe neurological disorder defined by spontaneous seizures. Current treatment options fail in a large proportion of patients, while questions as to the basic mechanisms of seizure initiation and propagation remain. Advances in… read more here.
Keywords: photon calcium; two photon; head fixed; calcium imaging ... See more keywords
A spherical treadmill system to train head-fixed adult rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2017.12.018
Abstract: BACKGROUND While spherical treadmills are widely used in mouse models, there are only a few experimental setups suitable for adult rats, and none of them include head-fixation. NEW METHOD We introduce a novel spherical treadmill… read more here.
Keywords: spherical treadmill; treadmill; head fixed; adult rats ... See more keywords
Efficient training approaches for optimizing behavioral performance and reducing head fixation time
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276531
Abstract: The use of head fixation has become routine in systems neuroscience. However, whether the behavior changes with head fixation, whether animals can learn aspects of a task while freely moving and transfer this knowledge to… read more here.
Keywords: head fixation; head; freely moving; training ... See more keywords
Coordination between Eye Movement and Whisking in Head-Fixed Mice Navigating a Plus Maze
Sign Up to like & getrecommendations! Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0089-22.2022
Abstract: Abstract Navigation through complex environments requires motor planning, motor preparation, and the coordination between multiple sensory–motor modalities. For example, the stepping motion when we walk is coordinated with motion of the torso, arms, head, and… read more here.
Keywords: movement; fixed mice; eye movement; eye ... See more keywords