Metabolic Labeling of Glycerophospholipids via Clickable Analogs Derivatized at the Lipid Headgroup.
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2020.104971
Abstract: Metabolic labeling, in which substrate analogs containing diminutive tags can infiltrate biosynthetic pathways and generate labeled products in cells, has led to dramatic advancements in the means by which complex biomolecules can be detected and… read more here.
Keywords: clickable analogs; glycerophospholipids via; headgroup; labeling glycerophospholipids ... See more keywords
Comparison of Carboxybetaine with Sulfobetaine as Lipid Headgroup Involved in Intermolecular Interaction between Lipids in the Membrane
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DOI: 10.1021/acsomega.7b00574
Abstract: Diacylglycerides (DAGs) constitute an important category of lipids owing to their ability to form a lipid membrane, which can be used in a wide variety of biomedical applications. DAGs often include a zwitterionic polar headgroup… read more here.
Keywords: headgroup; dppc; dppc dpcb; intermolecular interaction ... See more keywords
Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy
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DOI: 10.1038/s41586-025-09246-x
Abstract: Decreased brain levels of coenzyme Q10 (CoQ10), an endogenously synthesized lipophilic antioxidant1,2, underpin encephalopathy in primary CoQ10 deficiencies3,4 and are associated with common neurodegenerative diseases and the ageing process5,6. CoQ10 supplementation does not increase CoQ10… read more here.
Keywords: mitochondrial encephalopathy; headgroup intermediates; coq10 headgroup; synthesis ... See more keywords