Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy
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DOI: 10.1038/s41586-025-09246-x
Abstract: Decreased brain levels of coenzyme Q10 (CoQ10), an endogenously synthesized lipophilic antioxidant1,2, underpin encephalopathy in primary CoQ10 deficiencies3,4 and are associated with common neurodegenerative diseases and the ageing process5,6. CoQ10 supplementation does not increase CoQ10… read more here.
Keywords: mitochondrial encephalopathy; headgroup intermediates; coq10 headgroup; synthesis ... See more keywords