Integrating neuroimaging biomarkers into the multicentre, high-dose erythropoietin for asphyxia and encephalopathy (HEAL) trial: rationale, protocol and harmonisation
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DOI: 10.1136/bmjopen-2020-043852
Abstract: Introduction MRI and MR spectroscopy (MRS) provide early biomarkers of brain injury and treatment response in neonates with hypoxic-ischaemic encephalopathy). Still, there are challenges to incorporating neuroimaging biomarkers into multisite randomised controlled trials. In this… read more here.
Keywords: heal trial; neuroimaging biomarkers; trial; dose erythropoietin ... See more keywords