Bone fracture healing is delayed in splenectomic rats
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DOI: 10.1016/j.lfs.2016.12.005
Abstract: Aims: Splenectomy is sometimes required in bone fracture patients. The present study aims to investigate the effect of splenectomy on fracture healing in rats. Main methods: Rats underwent osteotomy were subjected to splenectomy. The effects… read more here.
Keywords: fracture site; bone fracture; fracture; expression ... See more keywords
Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling
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DOI: 10.7554/elife.75753
Abstract: Amino-terminal fragments from proteolytically cleaved gasdermins (GSDMs) form plasma membrane pores that enable the secretion of interleukin-1β (IL-1β) and IL-18. Excessive GSDM-mediated pore formation can compromise the integrity of the plasma membrane thereby causing the… read more here.
Keywords: fracture; healing delayed; mice; fracture healing ... See more keywords