Antioxidant Silk Fibroin Composite Hydrogel for Rapid Healing of Diabetic Wound.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200097
Abstract: Wound healing is a complex process requiring multiple biological pathways and chemical responses to be activated and synchronized to recover tissue integrity. In normal physiological circumstances, the epidermal barrier restoration process through new tissue formation… read more here.
Keywords: healing diabetic; hydrogel; silk fibroin; composite hydrogel ... See more keywords
fMaggot treatment promotes healing of diabetic foot ulcer wounds possibly by upregulating Treg levels.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2021.109187
Abstract: PURPOSE Through the study of regulatory T cells (Tregs), we found a possible way to promote the healing of diabetic foot ulcers (DFUs) with maggot treatment and investigated the associated mechanism. METHODS Immunohistochemistry was used… read more here.
Keywords: healing diabetic; diabetic foot; treated without; mdt ... See more keywords
Melatonin loaded lecithin-chitosan nanoparticles improved the wound healing in diabetic rats.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.08.027
Abstract: Wound healing in diabetic patients remains a worldwide problem that can cause amputations and even lead to death. This work aimed to produce lecithin-chitosan nanoparticles loaded with melatonin (MEL-NP) incorporated in a topical formulation to… read more here.
Keywords: wound healing; chitosan nanoparticles; lecithin chitosan; healing diabetic ... See more keywords
Efficiency and Safety of Dextran-PAMAM/siMMP-9 Complexes for Decreasing Matrix Metalloproteinase-9 Expression and Promoting Wound Healing in Diabetic Rats.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00487
Abstract: Difficult healing of diabetic foot ulcers is associated with overexpression of matrix metalloproteinase 9 (MMP-9) in the local wound. Therefore, strategies aimed at downregulation of MMP-9 levels in ulcer sites may promote tissue regeneration and… read more here.
Keywords: healing diabetic; pamam simmp; dextran pamam; dextran ... See more keywords
Electrospun multifunctional nanofibrous mats loaded with bioactive anemoside B4 for accelerated wound healing in diabetic mice
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2021.2021319
Abstract: Abstract With the worldwide prevalence of diabetes and considering the complicated microenvironment of diabetic wounds, the design and development of innovative multifunctional wound dressing materials are much wanted for the treatment of hard-to-heal wounds in… read more here.
Keywords: healing diabetic; wound healing; nanofibrous mats; pva ane ... See more keywords
Thioctamer: a novel thioctic acid–glatiramer acetate nanoconjugate expedites wound healing in diabetic rats
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2081382
Abstract: Abstract The current work aims to design thioctic acid (TA) and glatiramer acetate (GA) nanoconjugate (thioctamer) loaded hydrogel formula as well as evaluation of thioctamer preclinical efficacy in expediting wound healing in a rat model… read more here.
Keywords: healing diabetic; diabetic rats; wound healing; thioctic acid ... See more keywords
Blocking RAGE improves wound healing in diabetic pigs
Sign Up to like & getrecommendations! Published in 2022 at "International Wound Journal"
DOI: 10.1111/iwj.13909
Abstract: Receptor for Advanced Glycated End‐products (RAGE) is highly expressed in diabetes and impairs wound healing. We proposed that administering an antibody that blocks RAGE will hasten the healing of dorsal wounds in diabetic pigs compared… read more here.
Keywords: healing diabetic; pig; wound healing; diabetic pigs ... See more keywords
Roxadustat promotes angiogenesis through HIF‐1α/VEGF/VEGFR2 signaling and accelerates cutaneous wound healing in diabetic rats
Sign Up to like & getrecommendations! Published in 2019 at "Wound Repair and Regeneration"
DOI: 10.1111/wrr.12708
Abstract: Diabetic foot ulcers are a major health‐care burden worldwide. One primary cause of the delayed wound healing in diabetic patients is impaired function of the hypoxia‐inducible factor‐1α/vascular endothelial growth factor (HIF‐1α/VEGF) axis, which results in… read more here.
Keywords: hif vegf; wound healing; healing diabetic; roxadustat ... See more keywords
Non-healing ‘diabetic’ ulceration which turned out to be a lentiginous melanoma: a case from a diabetic foot clinic
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2018-228649
Abstract: There are currently 425 million of people with diabetes worldwide[1][1] and diabetic foot disease affects approximately 6% of them.[2][2] Any skin lesion in a person with a history of diabetes should be, however, reviewed with an… read more here.
Keywords: healing diabetic; case; diabetic ulceration; non healing ... See more keywords
Astragalus Polysaccharides Promote Wound Healing in Diabetic Rats by Upregulating PETN and Inhibiting the mTOR Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/3459102
Abstract: Objective Presently, astragalus polysaccharide (APS) is being investigated for its therapeutic potential in various diseases; however, its underlying mechanism has not yet been clarified. This study was aimed at observing the effects of APS on… read more here.
Keywords: healing diabetic; diabetic rats; wound healing; mtor pathway ... See more keywords
Novel Curcumin-Encapsulated α-Tocopherol Nanoemulsion System and Its Potential Application for Wound Healing in Diabetic Animals
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/7669255
Abstract: Objective This project was aimed at formulating a novel nanoemulsion system and evaluating it for open incision wound healing in diabetic animals. Methods The nanoemulsions were characterized for droplet size and surface charge, drug content,… read more here.
Keywords: healing diabetic; wound healing; diabetic animals; nanoemulsion ... See more keywords