Non-Healing Perianal Fistulas: A Clinical Model of Tissue Senescence Impairing Both Tissue Fibrosis and Regenerative Potential
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DOI: 10.3390/biomedicines11020537
Abstract: Senescent cells and fibrosis are important components that impact the regenerative capacity of skin, particularly when considering chronic non-healing wounds. Anoderm and perianal fistulas in the setting of Crohn’s disease are clinically pathophysiological extremes with… read more here.
Keywords: non healing; healing perianal; perianal fistulas; senescence ... See more keywords