Macrophage efferocytosis in health and disease
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3780
Abstract: Creating cellular homeostasis within a defined tissue typically relates to the processes of apoptosis and efferocytosis. A great example here is cell debris that must be removed to prevent unwanted inflammatory responses and then reduce… read more here.
Keywords: efferocytosis; macrophage efferocytosis; efferocytosis health; health disease ... See more keywords
Osteoblast Lineage Support of Hematopoiesis in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4678
Abstract: In mammals, hematopoiesis migrates to the bone marrow during embryogenesis coincident with the appearance of mineralized bone, where hematopoietic stem cells (HSCs) and their progeny are maintained by the surrounding microenvironment or niche, and sustain… read more here.
Keywords: health disease; hematopoiesis health; hematopoiesis; osteoblast lineage ... See more keywords
Interplay between the miRNome and the epigenetic machinery: Implications in health and disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25819
Abstract: Epigenetics refers to functionally relevant genomic changes that do not involve changes in the basic nucleotide sequence. Majorly, these are of two types: DNA methylation and histone modifications. Small RNA molecules called miRNAs are often… read more here.
Keywords: machinery; mir; health disease; methylation histone ... See more keywords
Health and disease, an orchestra of three players: Serotonin, orexins, and nitric oxide
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24030
Abstract: Over the past century, a huge amount of evidence has emerged pointing to the role of the neurotransmitter serotonin, the neuropeptides orexin A and B, and the small gaseous molecule nitric oxide (NO) (Fig. 1)… read more here.
Keywords: serotonin orexins; three players; disease; health disease ... See more keywords
Analyzing Ribosome Remodeling in Health and Disease
Sign Up to like & getrecommendations! Published in 2020 at "PROTEOMICS"
DOI: 10.1002/pmic.202000039
Abstract: Increasing evidence suggests that ribosomes actively regulate protein synthesis. However, much of this evidence is indirect, leaving this layer of gene regulation largely unexplored, in part due to methodological limitations. Indeed, evidence is reviewed demonstrating… read more here.
Keywords: analyzing ribosome; ribosome remodeling; evidence; health disease ... See more keywords
Immunotoxicity of nanomaterials in health and disease: Current challenges and emerging approaches for identifying immune modifiers in susceptible populations
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology"
DOI: 10.1002/wnan.1804
Abstract: Abstract Nanosafety assessment has experienced an intense era of research during the past decades driven by a vivid interest of regulators, industry, and society. Toxicological assays based on in vitro cellular models have undergone an… read more here.
Keywords: toxicology; health; immunotoxicity nanomaterials; disease current ... See more keywords
Immunohistochemistry of Human Hsp60 in Health and Disease: From Autoimmunity to Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7477-1_21
Abstract: Hsp60 (also called Cpn60) is a chaperonin with essential functions for cell physiology and survival. Additionally, its involvement in the pathogenesis of a variety of diseases (e.g., some autoimmune disorders and cancer) is becoming evident… read more here.
Keywords: immunohistochemistry human; human hsp60; disease autoimmunity; health disease ... See more keywords
Ceramide Domains in Health and Disease: A Biophysical Perspective.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-21162-2_6
Abstract: Ceramides are the central molecules in sphingolipid metabolism. In addition, they are recognized as important modulators of cell function, playing key roles in several cellular processes that range from cell proliferation to cell death. Moreover,… read more here.
Keywords: ceramide domains; disease biophysical; domains health; health disease ... See more keywords
Novel Models to Study Stromal Cell-Leukocyte Interactions in Health and Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-78127-3_8
Abstract: To study human immunology in general and stromal immunology in particular, it is highly motivated to move from monolayers to 3D cultures, such as organotypic models, that better mimic the function of living tissue. These… read more here.
Keywords: stromal cell; health disease; disease; immunology ... See more keywords
Role of the chanzyme TRPM7 in the nervous system in health and disease
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03124-2
Abstract: The channel kinase (chanzyme) transient receptor potential melastatin-like 7 (TRPM7) has a unique dual protein structure composed of an ion channel with an α-kinase domain on its C-terminus. In the nervous system, under physiological conditions,… read more here.
Keywords: nervous system; health disease; channel kinase;
Human Microbiome in Health and Disease: The Good, the Bad, and the Bugly
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06059-y
Abstract: Ask a group of medical professionals and scientists what is the “hottest” area of investigation today, or to suggest a topic for a forum or symposium and the likely answer will be “the microbiome.” A… read more here.
Keywords: disease good; health disease; microbiome health; human microbiome ... See more keywords