Brazilian propolis promotes immunomodulation on human cells from American Tegumentar Leishmaniasis patients and healthy donors infected with L. braziliensis.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2016.09.014
Abstract: American Tegumentar Leishmaniasis (ATL) is an infectious disease caused by Leishmania parasites with ineffective treatment. The properties of propolis have been studied in different experimental studies, however, few works have investigated the effects of propolis… read more here.
Keywords: american tegumentar; leishmaniasis; braziliensis; propolis ... See more keywords
Tuberculosis patients display a high proportion of CD8+ T cells with a high cytotoxic potential
Sign Up to like & getrecommendations! Published in 2019 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12724
Abstract: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) and remains a major cause of morbidity and mortality worldwide. In the host's immune response system, T cells play a critical role in mediating… read more here.
Keywords: cd8; cd8 cells; tuberculosis patients; healthy donors ... See more keywords
Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool.
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DOI: 10.1111/imm.13645
Abstract: Citrullination and homocitrullination are stress induced post-translational modifications (siPTMs) which can be recognized by T cells. Peripheral blood mononuclear cells isolated from healthy donors and rheumatoid arthritis (RA) patients were stimulated with nine siPTM-peptides. CD45RA/CD45RO… read more here.
Keywords: healthy donors; immune responses; hla; peptides siptm ... See more keywords
KIR genotype and haplotype repertoire in Kuwaiti healthy donors, hematopoietic cell transplant recipients and healthy family members.
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DOI: 10.1111/tan.15029
Abstract: The gene complex located on chromosome 19q13.4 encodes the Killer-cell Immunoglobulin-like Receptors (KIRs), which exhibit remarkable polymorphism in both gene content and sequences. Further, the repertoire of KIR genes varies within and between populations, creating… read more here.
Keywords: healthy donors; hematopoietic cell; repertoire; gene ... See more keywords
Abstract B68: Pre-existing immune memory to cancer-associated phosphopeptides in healthy donors
Sign Up to like & getrecommendations! Published in 2020 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm18-b68
Abstract: Identifying appropriate antigens is essential to developing effective cancer vaccines. Protein phosphorylation plays a major role in signal transduction pathways that are dysregulated and contribute to the malignant phenotype of cancer cells. Our lab has… read more here.
Keywords: associated phosphopeptides; cancer associated; memory; healthy donors ... See more keywords
On Demand Plerixafor As a Rescue Strategy in Healthy Donors to Achieve Adequate Stem Cells - a Pilot Study from South India
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DOI: 10.1182/blood-2019-127045
Abstract: Aims & Objectives: The aim of the study is to check the safety and feasibility of using Plerixafor in healthy donors who have failed to mobilise > 2 x 10 6/kg of CD34 cells on… read more here.
Keywords: pilot study; healthy donors; study; blood ... See more keywords
CD4 T cells specific for factor VIII are present at high frequency in healthy donors and comprise naïve and memory cells.
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DOI: 10.1182/bloodadvances.2017008706
Abstract: We investigated the frequency and subset origin of circulating factor VIII (FVIII)-specific CD4 T cells in healthy donors. Total CD4 T cells and purified CD4 T-cell subsets were stimulated with FVIII-loaded autologous dendritic cells and… read more here.
Keywords: cells specific; cd4 cells; frequency; healthy donors ... See more keywords
DIFFERENTIAL EXPRESSION PATTERN OF AIP, UCKL1, AND PKN1 GENES IN PROSTATE CANCER PATIENTS.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental oncology"
DOI: 10.32471/exp-oncology.2312-8852.vol-44-no-1.17380
Abstract: BACKGROUND The evolution of research on the therapy of prostate cancer (PC) depends on a study of molecules that are involved in the progression of this disease. Nevertheless, there is a need for additional biomarkers… read more here.
Keywords: prostate cancer; healthy donors; aip uckl1; pkn1 genes ... See more keywords
Peripheral Blood Stem Cell Mobilization in Healthy Donors by Granulocyte Colony-Stimulating Factor Causes Preferential Mobilization of Lymphocyte Subsets
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DOI: 10.3389/fimmu.2018.00845
Abstract: Background Allogeneic hematopoietic stem cell transplantation is associated with a high risk of immune-mediated post-transplant complications. Graft depletion of immunocompetent cell subsets is regarded as a possible strategy to reduce this risk without reducing antileukemic… read more here.
Keywords: preferential mobilization; healthy donors; stem cell; mobilization ... See more keywords
Specific circulating neutrophils subsets are present in clinically stable adults with cystic fibrosis and are further modulated by pulmonary exacerbations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1012310
Abstract: The progressive lung destruction in cystic fibrosis (CF) is tightly associated with chronic bacterial infection and neutrophil-dominated airway inflammation. CF pulmonary disease is complicated by episodes of acute exacerbations, contributing to irreversible lung damage. We… read more here.
Keywords: healthy donors; clinically stable; pulmonary exacerbations; stable adults ... See more keywords
CTLs From Patients With Atherosclerosis Show Elevated Adhesiveness and Distinct Integrin Expression Patterns on 2D Substrates
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.891916
Abstract: Atherosclerosis is the major cause of cardiovascular disease that is characterized by plaque formation in the blood vessel wall. Atherosclerotic plaques represent sites of chronic inflammation with diverse cell content that is shifted toward the… read more here.
Keywords: patients atherosclerosis; integrin expression; healthy donors; expression ... See more keywords