In vivo reproducibility of 3D relayed NOE in the healthy human brain at 7 T
Sign Up to like & getrecommendations! Published in 2023 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29600
Abstract: Nuclear Overhauser effect (NOE) is based on dipolar cross‐relaxation mechanism that enables the indirect detection of aliphatic protons via the water proton signal. This work focuses on determining the reproducibility of NOE magnetization transfer ratio… read more here.
Keywords: vivo reproducibility; human brain; relayed noe; healthy human ... See more keywords
Phosphorus MRS of healthy human spleen
Sign Up to like & getrecommendations! Published in 2022 at "Nmr in Biomedicine"
DOI: 10.1002/nbm.4779
Abstract: Phosphorus (31P‐) MRS in vivo enables detection and quantification of important phosphorus‐containing metabolites in biological tissues. 31P‐MRS of the normal spleen is challenging due to the relatively small volume and the larger distance between the… read more here.
Keywords: healthy human; 31p mrs; phosphorus; phosphorus mrs ... See more keywords
In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous delta-9-tetrahydrocannabinol fail to produce antinociceptive effects in healthy human volunteers
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05595-9
Abstract: Animal studies and anecdotal human reports suggest that cannabinoids have antinociceptive effects. Controlled human studies have produced mixed results. We sought to reduce existing variability by investigating the effects of intravenous delta-9-tetrahydrocannabinol (THC) in several… read more here.
Keywords: healthy human; antinociceptive effects; study; delta tetrahydrocannabinol ... See more keywords
Regional biomechanical and failure properties of healthy human ascending aorta and root.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2021.104705
Abstract: PURPOSE Aortic dissection (AD) is a life-threatening event that occurs when the intimal entry tear propagates and separates inner from outer layers of the aorta. Diameter, the current criterion for aneurysm repair, is far from… read more here.
Keywords: healthy human; properties healthy; human ascending; failure stresses ... See more keywords
Investigating the Role of the Reduced Solubility of the Pirfenidone-Fumaric Acid Cocrystal in Sustaining the Release Rate from Its Tablet Dosage Form by Conducting Comparative Bioavailability Study in Healthy Human Volunteers.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00052
Abstract: Pirfenidone (PFD) is the first pharmacological agent approved by the US Food and Drug Administration (FDA) in 2014 for the treatment of idiopathic pulmonary fibrosis (IPF). The recommended daily dosage of PFD in patients with… read more here.
Keywords: formulation; healthy human; dosage; comparative bioavailability ... See more keywords
Biodistribution and radiation dosimetry of the positron emission tomography probe for AMPA receptor, [11C]K-2, in healthy human subjects
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81002-3
Abstract: [11C]K-2, a radiotracer exhibiting high affinity and selectivity for α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), is suitable for the quantification of AMPARs in living human brains and potentially useful in the identification of epileptogenic foci in… read more here.
Keywords: radiation dose; healthy human; human subjects; 11c healthy ... See more keywords
Bacterial associations in the healthy human gut microbiome across populations
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82449-0
Abstract: In a microbial community, associations between constituent members play an important role in determining the overall structure and function of the community. The human gut microbiome is believed to play an integral role in host… read more here.
Keywords: healthy human; human gut; across populations; bacterial associations ... See more keywords
1400. Mass Balance, Metabolism, and Excretion of [14C]-Plazomicin in Healthy Human Subjects
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1231
Abstract: Abstract Background Plazomicin is a next-generation aminoglycoside (AG) with a structure that protects it from common AG resistance mechanisms in Enterobacteriaceae, and with in vitro activity against extended spectrum β-lactamase-producing and carbapenem-resistant Enterobacteriaceae. The purpose… read more here.
Keywords: healthy human; plazomicin healthy; mass; 14c plazomicin ... See more keywords
Efficacy and safety of topical depigmenting agent in healthy human fair skin female volunteers: A single‐arm study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12435
Abstract: Skin hyperpigmentation is the darkening of skin due to the increased production of melanin in the body. read more here.
Keywords: healthy human; efficacy safety; topical depigmenting; safety topical ... See more keywords
Individual cell motion in healthy human skin microvasculature by reflectance confocal video microscopy
Sign Up to like & getrecommendations! Published in 2020 at "Microcirculation"
DOI: 10.1111/micc.12621
Abstract: To describe upper dermal microvasculature of healthy human skin in terms of density and size of cutaneous blood vessels, leukocyte velocity, and leukocyte interactions with the endothelium. read more here.
Keywords: microvasculature; healthy human; microscopy; individual cell ... See more keywords
Staphylococcal Corneocyte Adhesion: Assay Optimization and Roles of Aap and SasG Adhesins in the Establishment of Healthy Skin Colonization
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02469-22
Abstract: The skin is the largest organ of the human body and acts as a shield against hazards such as harmful bacteria like Staphylococcus aureus. A diverse skin microbiota and immune cross talk control S. aureus… read more here.
Keywords: adhesion; skin; healthy human; healthy skin ... See more keywords