Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents
Sign Up to like & getrecommendations! Published in 2020 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abb8086
Abstract: Optogenetic hearing restoration in rodents by LED-based multichannel optical cochlear implants provides improved spectral selectivity. Honing hearing restoration Cochlear implants provide the brain with auditory information as a treatment for hearing impairment, but electrical implants… read more here.
Keywords: improved spectral; stimulation; spectral selectivity; cochlear implants ... See more keywords
Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice
Sign Up to like & getrecommendations! Published in 2022 at "Life Science Alliance"
DOI: 10.26508/lsa.202101338
Abstract: This longitudinal study revealed stable expression of the fast-gating channelrhodopsin f-Chrimson in cochlear neurons of mice over at least 2 yr upon a single postnatal AAV dosing of the cochlea. AAV-mediated optogenetic neural stimulation has… read more here.
Keywords: aav mediated; aav; hearing restoration; expression ... See more keywords