Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology
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DOI: 10.1002/ejhf.1029
Abstract: There is an unmet need for effective treatment strategies to reduce morbidity and mortality in patients with heart failure with preserved ejection fraction (HFpEF). Until recently, attention in patients with HFpEF was almost exclusively focused… read more here.
Keywords: heart; heart dysfunction; cardiology; right heart ... See more keywords
Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice
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DOI: 10.1093/cvr/cvz119
Abstract: Aims Lipotoxic cardiomyopathy in diabetic and obese patients typically encompasses increased cardiac fatty acid (FA) uptake eventually surpassing the mitochondrial oxidative capacity. Lowering FA utilization via inhibition of lipolysis represents a strategy to counteract the… read more here.
Keywords: heart; heart dysfunction; lipolysis; mice ... See more keywords
Right and left heart dysfunction predict mortality in pulmonary hypertension
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DOI: 10.1111/cpf.12266
Abstract: In pulmonary hypertension (PH), the right heart dysfunction is a strong predictor of adverse clinical outcome, while the role of the left heart is not fully determined. The aim of this study was to identify… read more here.
Keywords: heart; heart dysfunction; left heart; mortality ... See more keywords
Right Heart Dysfunction in Adults With Coarctation of Aorta: Prevalence and Prognostic Implications.
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DOI: 10.1161/circimaging.121.013075
Abstract: BACKGROUND Chronic elevation of left heart filling pressure causes pulmonary vascular remodeling, pulmonary hypertension, and right heart dysfunction. Although diastolic dysfunction is relatively common in patients with coarctation of aorta, there are limited data about… read more here.
Keywords: right heart; heart; coarctation aorta; heart dysfunction ... See more keywords
Clinically inapparent right heart dysfunction is associated with reduced myofilament force development in coronary artery disease
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DOI: 10.1186/s12872-021-01926-6
Abstract: Background Right ventricular dysfunction after CABG is associated with poor peri- and postoperative outcomes. We aimed to identify clinical and experimental predictors for preoperative inapparent right ventricular dysfunction and therefore hypothesized that reduced myofilament force… read more here.
Keywords: heart dysfunction; inapparent right; dysfunction; right heart ... See more keywords