Versatile human cardiac tissues engineered with perfusable heart extracellular microenvironment for biomedical applications
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-46928-y
Abstract: Engineered human cardiac tissues have been utilized for various biomedical applications, including drug testing, disease modeling, and regenerative medicine. However, the applications of cardiac tissues derived from human pluripotent stem cells are often limited due… read more here.
Keywords: cardiac tissues; biomedical applications; culture; human cardiac ... See more keywords
Three-dimensional heart extracellular matrix enhances chemically induced direct cardiac reprogramming
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn5768
Abstract: Direct cardiac reprogramming has emerged as a promising therapeutic approach for cardiac regeneration. Full chemical reprogramming with small molecules to generate cardiomyocytes may be more amenable than genetic reprogramming for clinical applications as it avoids… read more here.
Keywords: heart extracellular; extracellular matrix; three dimensional; direct cardiac ... See more keywords