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   Articles with "heart phagolysosomal" as a keyword



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High Cholesterol at the Heart of Phagolysosomal Damage.

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recommendations! Published in 2018 at "Cell metabolism"

DOI: 10.1016/j.cmet.2018.02.015

Abstract: Phagolysosome membrane rupture can trigger a maladaptive immune response that promotes tissue damage. In Science, Cantuti-Castelvetri et al. (2018) report that cholesterol-rich myelin debris overwhelms reverse cholesterol transport in aged phagocytes, leading to cholesterol crystal formation,… read more here.

Keywords: phagolysosomal damage; cholesterol; damage; heart phagolysosomal ... See more keywords