Autophagy activation can partially rescue proteasome dysfunction‐mediated cardiac toxicity
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DOI: 10.1111/acel.13715
Abstract: The ubiquitin–proteasome pathway and its functional interplay with other proteostatic and/or mitostatic modules are crucial for cell viability, especially in post‐mitotic cells like cardiomyocytes, which are constantly exposed to proteotoxic, metabolic, and mechanical stress. Consistently,… read more here.
Keywords: toxicity; dysfunction; heart targeted; proteasome dysfunction ... See more keywords