Characterisation of the single-cell human cardiomyocytes taken from the excess heart tissue of the right ventricular outlet in congenital heart disease.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue banking"
DOI: 10.1007/s10561-021-09970-4
Abstract: Cardiovascular disease is the second highest cause of death across the globe. Myocardial infarction is one of the heart diseases that cause permanent impairment of the heart wall leads to heart failure. Cellular therapy might… read more here.
Keywords: excess heart; heart; right ventricular; tissue ... See more keywords
Decellularization of porcine heart tissue to obtain extracellular matrix based hydrogels.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2019.11.023
Abstract: The use of hydrogels derived from the extracellular matrix (ECM) in tissue engineering applications aims to overcome the conundrum of mimicking the complexity of ECM composition in vitro. In this chapter, we describe a method… read more here.
Keywords: porcine heart; extracellular matrix; tissue; heart tissue ... See more keywords
Degradation of AIF in mouse heart tissue for estimating postmortem interval (PMI)
Sign Up to like & getrecommendations! Published in 2017 at "Forensic Science International: Genetics Supplement Series"
DOI: 10.1016/j.fsigss.2017.09.224
Abstract: Abstract Estimating time of death in forensic routines is particularly important, and a range of time can be determined by traditional methods Degradation of mRNA has been used to estimate postmortem interval (PMI) and many… read more here.
Keywords: degradation; pmi; postmortem interval; time ... See more keywords
SARS-CoV-2 detection and sequencing in heart tissue associated with myocarditis and persistent arrhythmia: A case report
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DOI: 10.1016/j.idcr.2021.e01187
Abstract: Background SARS-CoV-2 uses the human cell receptor angiotensin-converting enzyme (ACE2). ACE2 is widely present in the cardiovascular system including the myocardium and the conduction system. COVID-19 patients that present severe symptoms have been reported to… read more here.
Keywords: detection; case; report; heart tissue ... See more keywords
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abd1817
Abstract: A dynamic mechanical loading platform was developed to improve contractility of engineered heart tissues and study cardiac disease progression. Enhancing EHT platforms Although several engineered heart tissue (EHT) systems have been developed, most are not… read more here.
Keywords: dynamic loading; heart; engineered heart; disease ... See more keywords
Insights into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia from Engineered Human Heart Tissue.
Sign Up to like & getrecommendations! Published in 2019 at "Circulation"
DOI: 10.1161/circulationaha.119.039711
Abstract: BACKGROUND Modeling of human arrhythmias using induced pluripotent stem cell-derived cardiomyocytes has focused on single cell phenotypes. However, arrhythmias are the emergent properties of cells assembled into tissues, and the impact of inherited arrhythmia mutations… read more here.
Keywords: heart tissue; human heart; catecholaminergic polymorphic; tissue ... See more keywords
CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007597
Abstract: CD8+ T lymphocytes play an important role in controlling infections by intracellular pathogens. Chemokines and their receptors are crucial for the migration of CD8+ T-lymphocytes, which are the main IFNγ producers and cytotoxic effectors cells.… read more here.
Keywords: cd8; cd8 cells; cruzi; heart tissue ... See more keywords
α-Gal immunization positively impacts Trypanosoma cruzi colonization of heart tissue in a mouse model
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0009613
Abstract: Chagas disease, caused by the parasite Trypanosoma cruzi, is considered endemic in more than 20 countries but lacks both an approved vaccine and limited treatment for its chronic stage. Chronic infection is most harmful to… read more here.
Keywords: immunization; heart; infection; heart tissue ... See more keywords
Investigation of the effects of aging on the expression of aquaporin 1 and aquaporin 4 protein in heart tissue
Sign Up to like & getrecommendations! Published in 2017 at "Anatolian Journal of Cardiology"
DOI: 10.14744/anatoljcardiol.2016.7033
Abstract: Objective: Aquaporin (AQP) 1 and AQP 4 are expressed in human heart and several studies have been focused on these two aquaporins. For this purpose, the present study is aimed to research the effects of… read more here.
Keywords: heart; effects aging; aquaporin; aqp1 aqp4 ... See more keywords
The effect of different digoxin concentrations on heart tissue and antioxidant status in iron-overloaded rats
Sign Up to like & getrecommendations! Published in 2018 at "ARYA Atherosclerosis"
DOI: 10.22122/arya.v14i2.1642
Abstract: BACKGROUND Thalassaemia is a hereditary disorder and has an economic burden on patients and the government. The most prevalent complication in these patients is iron overload which is followed by cardiomyopathy. Digoxin is considered as… read more here.
Keywords: iron; heart tissue; digoxin; iron overloaded ... See more keywords
Metabolic Acidosis Results in Sexually Dimorphic Response in the Heart Tissue
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13040549
Abstract: Metabolic acidosis (MA) is a highly prevalent disorder in a significant proportion of the population, resulting from imbalance in blood pH homeostasis. The heart, being an organ with very low regenerative capacity and high metabolic… read more here.
Keywords: metabolic acidosis; heart; heart tissue; low grade ... See more keywords