Dynamic Patterns of N6-Methyladenosine Profiles of Messenger RNA Correlated with the Cardiomyocyte Regenerability during the Early Heart Development in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/5537804
Abstract: N6-Methyladenosine (m6A) plays important roles in regulating mRNA processing. Despite rapid progress in this field, little is known about the role and mechanism of m6A modification in myocardial development and cardiomyocyte regeneration. Existing studies have… read more here.
Keywords: day old; heart; heart tissues; mice ... See more keywords
Contractility analysis of human engineered 3D heart tissues by an automatic tracking technique using a standalone application
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266834
Abstract: The use of Engineered Heart Tissues (EHT) as in vitro model for disease modeling and drug screening has increased, as they provide important insight into the genetic mechanisms, cardiac toxicity or drug responses. Consequently, this… read more here.
Keywords: heart tissues; standalone application; engineered heart; analysis ... See more keywords
Curcumin mediated attenuation of carbofuran induced toxicity in the heart of Wistar rats.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2017.63.6.3
Abstract: Carbofuran is used to improve the agricultural productivity as well as to protect the house hold and industrial products, but due to accumulation in the biological system, it causes serious side effects in many non-targets… read more here.
Keywords: heart; carbofuran; heart tissues; attenuation ... See more keywords
A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12020214
Abstract: Cardiomyocytes derived from human pluripotent stem cells (hPSC-CMs) hold a great potential as human in vitro models for studying heart disease and for drug safety screening. Nevertheless, their associated immaturity relative to the adult myocardium… read more here.
Keywords: heart tissues; platform; new versatile; heart ... See more keywords